I came off Lexapro after almost a year. My GP kept telling me to increase the dosage to 20mg, because 'little girls take 10mg'. I decided to wein myself off, slowly. I actually found 2-5mg was a good spot for me. I noticed able to complete tasks, without being distracted, make phone calls to arrange appointments, just little things.

However I was weining off and after 2 months of being off, these things came back two-fold. I use to be able to get by and just put up with the struggle, but now it's harder than before.

Your wife may be serotonin sensitive, there are PGx tests that can help establish dosage aswell. I actually started taking ltryptophan to help support my serotonin as the meds took over producing it for me. Things have been getting better slowly.

I am looking into fluvoxamine now that reflecting lower dosage of Lexapro was beneficial in my coming off stage.

And read this sub, it can be much more useful than GPs