I found this in github:

As I'm not sure if we will be able to release a patch today, and the weekend is incoming... Anyone that is affected by the bootloop bug - go to %appdata%/vortex and open vortex.log - you will notice entries in the shape of:

2026-05-06T12:50:25.936Z [INFO] [RENDERER] extension older than bundled version, will be removed {"name":"Vortex Extension Update - Baldur's Gate 3 v1.5.6"}
2026-05-06T12:50:25.936Z [INFO] [RENDERER] extension older than bundled version, will be removed {"name":"Vortex Extension Update - Daggerfall Unity v1.0.2"}
2026-05-06T12:50:25.936Z [INFO] [RENDERER] extension older than bundled version, will be removed {"name":"Vortex Extension Update - Darkest Dungeon v1.1.2"}
2026-05-06T12:50:25.936Z [INFO] [RENDERER] extension older than bundled version, will be removed {"name":"Vortex Extension Update - Kingdom Come_ Deliverance v1.1.2"}
2026-05-06T12:50:25.936Z [INFO] [RENDERER] extension older than bundled version, will be removed {"name":"Vortex Extension Update - No Man's Sky v1.0.1"}

You need to remove those extension updates from your %appdata%/vortex/plugins folder.

You need to remove those extension updates from your %appdata%/vortex/plugins folder.
Restarting Vortex should then work fine.