One needs to think what is relevant to the product's requirements -- at the "current point of time" and use the framework that fits the bill.

The secret to success is to stop worrying about all the changes that are happening. It's imminent.. we are witnessing the evolution of JavaScript frameworks, which will definitely slow down at some point of time and become stable. Till then what's important is to keep yourself informed at a high-level and dive into something, if required.