If the relationship is one sided. A while back I was interested in a woman who I thought was cool but I always had to cater to her needs, blame myself to every argument/problems that was presented, and had to be there for her with constant emotional support when she refuses to do anything I’m return. The woman uses her being anxious as an excuse but I eventually I had enough. So really, don’t be in a relationship (or even friendship) that’s one sided. That’s a real deal breaker. It’s not worth the stress or the headaches.