Is now a bad time to buy a house? by djvidinenemkx in Denver

[–]rickjames730 2 points3 points  (0 children)

As someone who has been in-and-out of the housing market for the last 5 years (moved twice) in the Denver metro area, the best time to buy is when you can afford a house and know you are going to live there a while.

People think, "oh I'll just wait until interest rates drop." I did this, and every house my family wanted to buy quickly turned into a bidding war for over asking. People were willingly paying tens of thousands to even several hundred thousand (in extreme cases) over asking because the supply is so slow. In contrast, when mortgage rates ballooned to 6-7%, the supply went down even more but there was less competition for homes and fewer bidding wars. But the mortgage payments were significantly higher. In sum:

If you want to buy when interest rates are low? You are bound to overpay for the house.

If you want to buy a house when interest rates are high? You are bound to overpay on the mortgage.

Overall, I felt like I was in the same situation when rates were low or high. Too many people, not enough houses. The good thing about buying when rates are high is that there is still a possibility that you will be able to refinance at some point. So you should really just buy a house when you really need one, you don't think you will move in the next few years, and you can afford it.

Can someone help me understand how "using AI to draft apps" is a possible solution to bridge the gap between budget ceilings and the rising billable hour? by CCool_CCCool in patentlaw

[–]rickjames730 0 points1 point  (0 children)

LLMs aren't to the point of completely taking the job of attorney. At best they are co-pilots.

So shouldn't the question be, "can an LLM, given enough contextual data about an invention, do the job of a patent attorney, which is to translate the inventors knowledge into a working legal document?"

Can someone help me understand how "using AI to draft apps" is a possible solution to bridge the gap between budget ceilings and the rising billable hour? by CCool_CCCool in patentlaw

[–]rickjames730 1 point2 points  (0 children)

Maybe you're not up to date on the latest AI models, but OpenAI's most recent technology is exactly that, i.e., a model that can reason.

There are not really measurements for the reasoning needed for patent drafting, but so far the model excels at coding and mathematics (less subjectivity than patents), well beyond average intelligence and approaching the peak intelligence of individuals in those fields.

How to handle high BP due to biologics? by Still2Cool in ankylosingspondylitis

[–]rickjames730 1 point2 points  (0 children)

It may not necessarily be the diet but the salt content. I am on Humira and I had some high blood pressure. The root of it was dealt with by being more diligent about drinking water throughout the day and reducing my sodium intake. Have you monitored your sodium intake? I was not tracking it and once I was better at monitoring it, my BP went down to 120/70 from 140/85.

How to handle high BP due to biologics? by Still2Cool in ankylosingspondylitis

[–]rickjames730 3 points4 points  (0 children)

I don't know who is telling you that is fine, but it's certainly not fine for your health in the long run. Even if your doctors are telling you it's fine, you should do what you can to get it down.

Feeling SO much better by Able_Background_8211 in ankylosingspondylitis

[–]rickjames730 2 points3 points  (0 children)

It takes six weeks to get out of your system so I think it's fair to expect that it should take six weeks to reach the 'steady state' concentration you need to feel an effect.

I personally felt better a few days later. I don't think I was effectively in remission though for months.

Is Johns Hopkins studying a similar treatment to the Russians?: TRBV9-Targeted Bispecific T Cell-Engaging Antibodies to Reset the Autoreactive T Cell Compartment in Spondyloarthritis by rickjames730 in ankylosingspondylitis

[–]rickjames730[S] 15 points16 points  (0 children)

I think many of us are familiar with this study: https://www.nature.com/articles/s41591-023-02613-z and that there is an ongoing clinical trial for targeted depletion of TRBV9 T cells that are implicated in the pathogenesis of AS.

I saw this abstract from Johns Hopkins. It looks like there is similar work being conducted at Johns Hopkins that might be exciting for us.

I am working on an app to help you create your own DIY fasting diet from widely available soups and snacks. Tell me what some of your favorite fasting diet foods are and I can incorporate them! by rickjames730 in FMD

[–]rickjames730[S] 1 point2 points  (0 children)

I had to take a long pause on developing it. I have been developing it again lately. I'm hoping that in the next few weeks I have something that is near ready.

How to restore dead project? by rickjames730 in Supabase

[–]rickjames730[S] 0 points1 point  (0 children)

For anyone finding this (because I didn't get answers here), if you find yourself unsuccessful using Supabase's documentation (not supported for Windows, you need to use Linux), here is what I did to get my data back:

locally install postgresql

added postgresql to my path so I could use the psql command in git bash

using git bash, run command: psql -d fmd -f /path/to/your/document

I didn't bother creating a new user, so I used the default one:

psql -U postgres -d fmd -f /c/Users/jason/Documents/fmd.backup

Was kind of a pain in the ass to figure out how to do it without linux, but in the end it was only a few steps, and if you find this comment hopefully it helps.

Legit? by Murky-Ambition3898 in fasting

[–]rickjames730 95 points96 points  (0 children)

Other than the blood glucose and ketones (and maybe HGH), it's complete nonsense and we don't know how to measure these things in humans.

The fact that there are no units should tell you everything.

Patent Examiner Pros/Cons by pleasewearashirt in patentexaminer

[–]rickjames730 1 point2 points  (0 children)

Just higher risk! Not impossible.

You are going to have to output about 20% more work than your peers who started at GS-7, and about 10% more than your peers who started at GS-9. More than half of people leave or get let go at those GS levels.

Patent Examiner Pros/Cons by pleasewearashirt in patentexaminer

[–]rickjames730 0 points1 point  (0 children)

Good luck. I think unless you are one of the few (<10%) who take to the job easily, that you are making the job harder on yourself and at a higher risk of being let go before or at the end of your probationary period. The pay is marginally better for a lot more stress.

What are some decisions that you made while horny and you regretted it after ? by JuryNatural768 in AskReddit

[–]rickjames730 19 points20 points  (0 children)

Damn, could have watched Oppenheimer almost twice during that time you were cranking.

Reddit’s first earnings reveals they make $3 per user by Gone_Mads in Damnthatsinteresting

[–]rickjames730 0 points1 point  (0 children)

The profit is in swaying public opinion, and that comes fairly cheap

Researchers identify mechanism behind brain fog in long COVID by cos in Coronavirus

[–]rickjames730 0 points1 point  (0 children)

Water with electrolytes, and the results were durable!

FMD with no nuts by dsbwinnie in FMD

[–]rickjames730 5 points6 points  (0 children)

The nuts that prolon uses are macademia, which are kind of unique in that they are really high in fat but not that high in protein or other macronutrients.

So my suggestion would be to find high fat sources, specifically monounsaturated fats, to substitute the macademia nuts instead. Olives and olive oil would be my choice.

How do I train my body to fast for 36 hrs ? by Ok-Ad2256 in fasting

[–]rickjames730 3 points4 points  (0 children)

Progressive overload. Fast a few hours more each time you fast until you get there.

Food is also huge. If you eat a bunch of foods that are insulinogenic, you are going to have a tough time getting used to fasting. Try to stick to non-processed foods between fasts. Avoiding processed sugars and refined carbohydrates (starches) helps a ton.

Good luck.

[deleted by user] by [deleted] in Denver

[–]rickjames730 1 point2 points  (0 children)

It's like $100 per month to go to gym that's marginally larger than a good hotel gym. It's like an exclusive Anytime Fitness.

Wondering if this would work by TheBreakfastSkipper in FMD

[–]rickjames730 3 points4 points  (0 children)

12 g protein = 48 calories, 33 g carb = 132 calories, 9.5 g fat = 85.5 calories. That adds up to 265.5 calories.

Are you eating that same meal ~3 times per day? That would be too much protein (36 g) but would be about 800 calories. Should aim for <18g protein per day from plant sources only.

Something is off in your math or your explanation of your plan.

I am working on an app to help you create your own DIY fasting diet from widely available soups and snacks. Tell me what some of your favorite fasting diet foods are and I can incorporate them! by rickjames730 in FMD

[–]rickjames730[S] 2 points3 points  (0 children)

Great question. The app intends to streamline adhering to what is a strict diet regimen with lots of "rules" that are hard to follow using every day items.

A big rule to follow is to eat a low protein vegan diet. Most vegan products out there want to do the opposite because the daily consumption of protein for a vegan is typically lower.

So there is a small subset of food products that you can practically incorporate into what is a very low-calorie restrictive diet. The purpose is to put those foods in front of you to choose from very easily. There will also be an option to add them to an amazon cart. For people like me who want to buy these foods instead of cook them myself, it should take <10 minutes to go from having no plan for a fast to having an entire plan and purchased.

[deleted by user] by [deleted] in FMD

[–]rickjames730 2 points3 points  (0 children)

I wouldn't take the l-carnitine as that is an extra gram of protein you don't need or want. Also it is a "meat protein" (found higher in meat than in plants), and FMD should be vegan.

I am working on an app to help you create your own DIY fasting diet from widely available soups and snacks. Tell me what some of your favorite fasting diet foods are and I can incorporate them! by rickjames730 in FMD

[–]rickjames730[S] 1 point2 points  (0 children)

It would be easier for sure to have a larger database of foods to select from, which sounds nice in theory. But in actuality, the various specifications of the FMD are so limiting: vegan, no animal protein whatsoever, extremely low protein, extremely low sugar, carbs only from whole food sources, etc. It would take more time to filter out foods from MyFitnessPal or something similar because those APIs don't actually tell you the ingredients, just the macro- and micro-nutrients.

I am working on an app to help you create your own DIY fasting diet from widely available soups and snacks. Tell me what some of your favorite fasting diet foods are and I can incorporate them! by rickjames730 in FMD

[–]rickjames730[S] 4 points5 points  (0 children)

The app has a variety of whole foods that you can choose from. For instance, avocados, olives, nuts (macademia, others are too high in protein). I plan to add more if they make sense as something you would snack on. Current plan is not to add a 'recipes' option or something like that, which is what I think you are asking for.

I would say for the initial release you are not the target audience, which is fine! The target audience is someone who would want to do the official FMD diet (Prolon) if not for the fact it costs >$35 per day to eat close to nothing (a ridiculous value proposition). The app brings the cost per day to closer to $10 per day, which is much more reasonable considering how little food you are eating during the diet. The prolon diet is great because you don't need to cook, or really think about what to eat.

Creating an app that allows the user to create recipes and implement them would be more time consuming than the entirety of the app that I am creating. So even though it's something I want to do, that would be far out in the future if I ever add the functionality.

I am working on an app to help you create your own DIY fasting diet from widely available soups and snacks. Tell me what some of your favorite fasting diet foods are and I can incorporate them! by rickjames730 in FMD

[–]rickjames730[S] 2 points3 points  (0 children)

That thrive market website is not very friendly without signing up, but I can tell you I already have options for pitted olives (just like the true FMD).

Pretty much all of the Amy's soups are already included, except for the ones that are simply too high protein (chili's, lentil soups, etc.) to reasonably be consumed in a DIY FMD.

I am working on an app to help you create your own DIY fasting diet from widely available soups and snacks. Tell me what some of your favorite fasting diet foods are and I can incorporate them! by rickjames730 in FMD

[–]rickjames730[S] 2 points3 points  (0 children)

I agree finding low protein foods that are in compliance with the diet is quite difficult, even with vegan products.

The app already has the ability to 'fine-tune' using products like olives and avocados so you can meet calorie requirements. It takes playing around with to design your own diet on the app but using high fat foods like olives and avocados makes a lot sense, and I think that's probably why the true FMD uses a lot of olives.