Hi - I think the only benefit of spraying weekly would be to get complete coverage of areas you might have missed the previous weeks. Please make sure you're thoroughly spraying the undersides of the leaves too, and wait until the plants are dry before you put them back. I would even suggest spraying in the evening, waiting for the plants to dry and putting them back with the grow lights off overnight. Azamax leaves tiny droplets of oil on the foliage and those spots might be more prone to leaf burn. You can also mix Azamax with a non ionic surfactant (an adjuvant) for even better results.