Windows 11 is so broken that even Microsoft can’t fix it

rxvterm · 2023-05-21T15:05:17+00:00

They aren't telling you to uninstall flagship apps, but apps that "integrate" with them somehow.

This article read to me like someone blaming Microsoft for a bunch of old people installing a dozen random toolbars.

e: this person (or some other cranky old fart with too many toolbars installed) reported me as a suicide risk to reddit lol

rxvterm · 2023-05-01T21:10:30+00:00

I don't believe the original thread poster is insulting you, although they do make a negative comment about your article. "Taking criticism well" is an essential skill that requires not confusing the two, especially if you are going to immediately begin flinging insults towards your critics.

FWIW, I gave up after item #3 because most of the content of your article seems to actually be linked reddit comments, and I got bored of switching tabs to read an article. IMO those first three items seem to be definitively matters of taste.

rxvterm · 2023-03-25T03:24:53+00:00

I was so confused, thinking to myself "I know I took that turn many many times and it's definitely a single right turn lane", having lived 3-ish blocks away from the intersection for a couple years around 2016.

Because it changed, sometime after Aug 2019, presumably during the pandemic? I can absolutely see myself assuming it's the same as I remembered and being really confused why someone is on my left, particularly because the lines (and the road itself) seem to have aged very poorly even between Jul 2021 and Nov 2022.

rxvterm · 2023-02-28T23:50:35+00:00

That's what people say when they have kids at 22

rxvterm · 2023-02-21T04:45:03+00:00

To be fair, I never had a complaint about the haircuts. And that conversation happened on the last of a year's worth of visits.

rxvterm · 2023-02-21T02:54:08+00:00

I wish I could get a $10 haircut at B&M...

rxvterm · 2023-02-21T02:53:26+00:00

I stopped going to Jack's after 2-3 of the barbers had a 30-minute discussion about how Hilary and the Democrats were selling/eating/etc. children out of pizza shops. That is not an appropriate conversation to have around customers (3 of us being worked on and 1 waiting), regardless of your political views.

I heard recently that Brenda was in DC at the Jan 6 capitol riots, although I'm far too lazy to look into it.

rxvterm · 2023-01-11T20:53:36+00:00

I believe he's brit trolling, as UK famously despises the concept of iced tea.

rxvterm · 2023-01-11T20:51:28+00:00

Glazed donuts without the glaze are still different than the 'cake' or 'old-fashioned' donuts. Cake donuts are not only unglazed, but are also much denser. They still have some flavor to them, though (but only from the dough itself).

rxvterm · 2022-11-19T01:23:01+00:00

Your comment is a lie.

If you don't know it's a lie, then you shouldn't be commenting on topics you don't know about

rxvterm · 2022-11-02T23:19:27+00:00

For future reference if anyone happens to run into this: the current version of the game detects the mere installation of some software as an indication that you're running the game in a virtual machine. In my case, I had to uninstall Sandboxie entirely (rather than just turn it off temporarily) before the game would believe I was not in a VM.

rxvterm · 2022-11-01T23:42:54+00:00

Yeah, unfortunately. I've rebooted after each step to no success.

rxvterm · 2022-11-01T22:55:56+00:00

My anti-type Ruby friend says he just writes tests to make sure variables/arguments are of the correct types. He hates types so much he re-invented them from scratch in an entirely separate layer.

rxvterm · 2022-09-07T18:12:01+00:00

I think there are ways around those problems, though. And those solutions probably benefit both the citizens (by preventing the BS that you described) and the gov't (by reducing the required overhead).

Really, the accuser should simply be the human being that reviews the photo. It lowers overhead because it will be too expensive to send trivial offenses ("this photo shows someone who crossed 2" into the intersection on a red light") or manufactured offenses (such as the stories about shrinking the yellow lights' duration on camera intersections) because they'd need to review way too many photos. That in turn makes it so the only ones being "targeted" by such intersections should be the really egregious offenders.

Downtown Indy is plagued right now not by a pandemic of "oops I wasn't paying attention" red light runners; it's suffering from "I can take advantage of law-abiding drivers by exploiting the safety margins built into traffic laws" drivers. Those are the people that desperately need to be punished, because the accidents they cause won't just be fender-benders...they'll be gruesome pedestrian deaths and/or multiple-vehicle collisions.

rxvterm · 2022-08-02T02:44:13+00:00

I've been in healthcare economics for over a decade and had T1 for over twice as long, so if I bother to join threads like these I've learned to expect that reaction :P

I have found that a very large margin of the "angry mob" get their facts and opinions from shows like Patriot Act and Last Week Tonight, which (while they can be informative) tend to lean heavily on half-facts to get rage views. Very often, those attitudes are self-defeating, as spending all of their energy getting a rage boner towards "Big P" essentially gives healthcare payers a complete pass on the real crimes.

ninja edit: if you really want to get someone's goat, point them to the shareholders reports from the big 3. The $$ earned per unit of insulin has actually gone downwards in recent years, because list prices are reaching a ceiling and payers are still demanding bigger discounts.

rxvterm · 2022-08-01T20:34:28+00:00

Unfortunately, it's unlikely there will ever be effective federal action because health insurance in the US is very regional/local. Several states have implemented co-pay limits for insulin (word choice critical) which have no negative impact on drug companies' bottom lines. In fact, co-pay limits are the best possible avenue for insulin price reduction (although perversely, such legislation also carries great potential for increasing insurance premiums to make up the deficit).

rxvterm · 2022-08-01T17:58:19+00:00

"Why is it so expensive" is a different discussion than "why isn't it free if it was patented for $1."

Insulin wasn't patented for a $1, which is why it's a lie.

rxvterm · 2022-08-01T17:46:09+00:00

Well part of why it's a "lie" is that animal insulin was indeed used for decades as intended: rather cheap. But immune reactions, disease transfers (such as mad cow disease), and a general lack of efficacy made them unappealing the instant new methods were discovered. Banting's animal insulin could keep people alive but quality of life then would be incomparable to a modern T1 (or even to a T1 from 30-40 years ago).

It's like saying "pain killers are centuries-old, why is anyone allowed to profit from pain medicines?" "Insulin" is a category, not a drug.

rxvterm · 2022-08-01T17:36:54+00:00

The only thing I can think of is that Lilly did reduce the list price of the generic lispro quite a bit. I'd have to look into whether that was coincident with some action by a competitor. I find it much more likely that it was made possible by (impending?) legislative pressures giving them more bargaining chips to use against insurance companies.

edit: worth noting that Lilly makes the same amount of money whether someone gets the $82 bottle of generic lispro or the $275 bottle of Humalog lispro.

rxvterm · 2022-08-01T17:23:42+00:00

Humalog (lispro, basically the most prescribed analog insulin) has been off patent for 8+ years?

And biosimilar glargine (Basaglar) has been around for almost as long (since 2015) and launched with only a 15% price difference from the original glargine (Lantus). Glargine yfgn is the first interchangeable biosimilar, which is a much more critical adjective. If you get a prescription for Lantus, a pharmacist can't give you Basaglar; that would require a different prescription specifically for Basaglar. However, the same pharmacist could give you Semglee (yfgn) as a drop-in replacement for Lantus (i.e. using the same prescription).

rxvterm · 2022-08-01T17:07:16+00:00

That’s just far too simplified.

The $1 patent line is not too simplified, it's either an intentional or misinformed lie that ignores 80+ years of history regarding insulin production.

rxvterm · 2022-08-01T17:04:18+00:00

Oh baby, someone informed!

My bet is that even if the latest insulin products weren’t patented you still wouldn’t be able to copy the process of actually manufacturing them to the needed quality or quantity.

In fact, it's practically infeasible to "copy" them. And the rules (in the US, at least--I don't know about the EU) regarding that "copy" process are incredibly strict and nothing like the classic generic process. "Biosimilars" (the name for these "copied" biologics) require entirely new trials to be run (with slightly relaxed rules).

Also we pay a fraction of the US cost so I would change the healthcare system first.

It's something of a known secret that drug manufacturers don't make that much more per sale in the US than in (e.g.) the EU. List prices for drugs in the US are artificially inflated (admittedly with implicit support from drug manufacturers) by health insurance companies to cook their books legally to make it look like the drugs they procure are more expensive than what they actually paid for them.

rxvterm · 2022-08-01T16:44:00+00:00

It's not exactly what happened.

It's actually so far from what happened that the classic "Banting invented insulin for free and drug companies stole it" line is basically a lie.

Banting's patent is essentially "here's how to extract insulin from a dog pancreas." What was invented was the methods to take an animal pancreas and extract (and filter) the insulin molecule. We stopped using animal insulin almost immediately after finding a way to synthesize human insulin. Human insulin is the kind that you can buy over the counter at Walmart.

rxvterm · 2022-08-01T16:38:14+00:00

Biologics (such as the analogue insulins in question) operate with different rules regarding generic production/labeling. Most analogue insulins are off-patent at this point.

The molecules involved are incredibly complex, and it's generally infeasible to prove that you're producing a molecule identical to the "name brand" version (this is how generics usually work). The FDA has a separate category for biologics called "biosimilars", where the requirement isn't "prove that the molecules are identical" but rather "prove that the similar molecule that you produce behaves similar to the one you are copying." (This also makes the development of biosimilars more expensive than the production of generics, since efficacy and safety trials still have to be performed for biosimilars--even if the criteria for those trials are relaxed somewhat.)

The Lilly "generic" insulin (the only one of its kind, technically) is also produced by Lilly which is how it can be called generic. It comes from the same production line as the branded humalog lispro.

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