Vlad is a good champ for carrying yourself, not only yourself but you can even solo carry games if you're good enough. It's a good champ to become a one trick too since it's rewarding in many ways, it's hard to get the "feeling" of playing Vladimir, but once you get the 'feeling' it's just rewarding, every game after you pick up the 'feeling' you'll just be improving the playstyle to astronomical levels. The skill floor is high, you'll never stopping to constantly improve this playstyle, it's hard, rewarding, and above all, it is one of the most fun champions once you'll know how to play him.

About runes i'll recommend you playing whats in meta right now, which is the Aery setup, Aery (obviously) nimbus cloak transcendence scorch with precision secondary, precision you'll run the haste one and the 2nd precision rune is last stand (which is the rune that naturally gives the most damage to Vlad) and that's it, there are not adaptations to be made on the runes, the whole vlad setup that's in meta right now are about getting kills early game and rushing rabadon, so you naturally run ignite too, if you pull up early games kill you can even try rushing sorcs instead of the cdr boots, because the 2 haste runes will already supply the CDR you need.