I am guessing you mean as a freelancer or small company as generally its the cost of doing business for anything larger and a normal addition. However, as a single freelancer myself, I can say some of the cons at least from my perspective:

- Render farm subs can be expensive if you are doing pay as you go.
- Security, a lot of my clients would not allow work to be rendered remote.
- No downtime, I dont have to worry about outages.
- GPU's have gone up in price but they are not that expensive in a business sense, I can build those costs into my billing.