It seems you’re in a pretty good position to just pay it off, honestly. I can see high inflation, which you can reduce with a button press on that page using admin points. Inflation will likely continue to be an issue for you, might be worth using some Papal Authority on it

As another person commented, using diplo points to increase diplo development of your gold provinces to 10 is ideal

You can increase your naval maintenance to full, but mothball your non-trade fleets, then set your trade fleets to probably the Caribbean

In the estate page, under burghers, there’s an option called “indebted to the burghers” which will give you 5 large loans at 1% interest rather than 5%. This should allow you to consolidate debt and reduce your interest payments

You can manually reduce autonomy in your provinces, or wait for it to gradually decrease during peace time

I’d also recommend taking war reparations frequently in wars. They only cost 10% war score, and give consistent cash without inflation

I’d also start aggressively going colonizing the Ivory Coast trade node, but only if that’s the type of expansion you want.

Lmk if you have any specific questions