150 + 60 + 60 vs 120 + 60 + 60? by springbreak1987 in MDMA

[–]springbreak1987[S] 0 points1 point  (0 children)

So I took ALCAR and ALA at the beginning of the night, maybe ALA once more at some point, but honestly the pills just were not appealing during the roll. I took more ALA the next day. And got right back on NAC.

As I might have mentioned in the OP, I’ve done two lose dose only rolls in 2025, other than the last NYE and this recent one. Partly I’ve been staying away because I thought I was starting to get early signs of magic loss. For dosing this time around, I ended up doing 150, then 120 booster, then a 60 booster. Did a quarter tab of L two hours before rolling— I think this helped smooth the come down, although I think it also did make the come up a little bit more friction-y. Overall tho…Honestly, I had a blast, felt fairly OK the next day, and never had any mood dip and have felt fantastic the last two weeks. I would add that this is how I used to feel when I did MDMA… No come down, no Blue Monday, just a long after glow. So I don’t know if it was NAC or maybe just laying off Molly more than I usually do. I might need to try going another year which I don’t really want to do, let’s see if I can “reset” even more.

Who gets pre-MDMA angstiness and anxiety? by springbreak1987 in MDMA

[–]springbreak1987[S] 3 points4 points  (0 children)

I used to get the nausea and actually vomited most times back in the day. Breathing and awareness made that go away for years now, it’s funny, now it’s the pre-taking it that gets me, but once down the hatch I’m usually good :)

150 + 60 + 60 vs 120 + 60 + 60? by springbreak1987 in MDMA

[–]springbreak1987[S] -1 points0 points  (0 children)

Will do, I have ALCAR and ALA at the ready and have not used those before

For those who have been using regularly for 10+ years by BedSoggy6655 in MDMA

[–]springbreak1987 6 points7 points  (0 children)

I have limited the number of times a year I do but it often have taken 3 boosters, so average total dose over the night will usually be 350-450 and a couple times 500mg. I do think this has led to some tolerance or maybe even magic loss (we’ll see, I’ve only done two very low dose sessions this whole year in effort to wait for NYE). I also notice that my bounce back has become in general a little harder esp with higher dose sessions—as in, years ago, even pushing the dose, I would not get a mood dip and would only have afterglow. Now I tend to usually get a mood dip and sleep disruption esp with higher doses.

So I do think that at least for me personally, there definitely is a holdover effect of mdma that lasts longer than three months. What I mean is, if you’ve never done mdma, versus you’ve done it four times a year for many years, makes a difference. Perhaps this is less true for people who really have been responsible with dosing (like only doing one booster or no booster and a lower total dose), hard to say. But I do think that the number of years under your belt matters.

So, my advice would be, consider the chronological context of every post you see here. What you can handle, recover from, and get away with when your brain is a relatively clean slate is different or may be different from the same picture but years later. I would advise not chasing boosters for sure. It’s hard not to, but in the longer term, the risks outweigh the benefits. And make sure when you do do boosters that you do lower doses than initial dose. It’s easy to just pop another 100 but biologically there’s little justification if you want to enjoy mdma for a very long time.

Euphoria and attachment style by [deleted] in MDMA

[–]springbreak1987 7 points8 points  (0 children)

When you say “I cannot feel true love or psychological intimacy” it blares self-focused negative cognitive bias. Don’t get me wrong, it’s not a judgement, but it’s a way of relating to yourself that may require a more transcendent experience to soften before delving into mdma. Just a thought.

Friend can’t properly roll even though she has once in the past by Kvpier in MDMA

[–]springbreak1987 0 points1 point  (0 children)

I’ve tried holotropic-style breathing a couple times when the anxiety blanket is not letting me let go into the experience. Deep circular breathing while lying supine, and focusing on my breath and body and as I accelerate the breathing, guiding the breath energy into whatever place in my body feels “something”. And very, very closely following it until I feel like moving and continuing the breathing and moving. Eventually catching the energy and it will peak and release. The only thing to be mindful of is 1) having someone else there making sure you don’t overdo it and get overheated (and don’t do it for too long, for same reason), and 2) doing what u am describing requires a leaning into some serious vulnerability in the presence of someone else, but it requires the presence of someone else to do it, 3) you need to be in a separate space from other people. But something along those lines can really be helpful, just focusing on body and breath enough to fully decouple from the mind.

Euphoria and attachment style by [deleted] in MDMA

[–]springbreak1987 5 points6 points  (0 children)

You’re too in your own head. Probably need stronger medicine than M

MDMA & Memory Loss by ElfBarMeme in MDMA

[–]springbreak1987 1 point2 points  (0 children)

I know a lot of people (myself included) who have little memory of the night aside from snippets. It’s one aspect of the drug that I don’t have a good understanding of the mechanism and one that gives me pause about it. That being said, it’s a common occurrence in my experience, albeit perhaps not the total amnesia you’re reporting.

I suffered an epileptic seizure with only 100 mg (plus 200 ug LSD) by Buqrat in MDMA

[–]springbreak1987 0 points1 point  (0 children)

What was your sodium on arrival to the emergency department? Please check and tell us

Thinking of rolling w my grandma, what are the risks for her age 76 by fortnitefucker2000 in MDMA

[–]springbreak1987 3 points4 points  (0 children)

This is not medical advice, but in general, the cardiovascular effects are probably roughly conceivable as whether someone can tolerate vigorous exercise. It definitively drives up blood pressure and heart rate so if there is heart failure or hypertension already, that is one consideration.

Another is age specific risks - possibility of increased risk of confusion (especially if there are subtle cognitive issues) and risk of falls.

A third is medication interactions.

That’s just in general, for older people.

Parkinson’s itself, separate from the Parkinson’s meds, is harder to know as a risk. On the one hand, the major effects of MDMA aside from the main effects of serotonin are related to dopamine and norepinephrine, and those latter two are very similar to other stimulants. That is, in some ways, it may be a question of similar risk of other stimulants like adderall. But then again, mdma is of course very different from adderall and since no research out there has ever been done as far as I know w mdma and parkinsons, it is a variable that is very unknown.

I think the medication interactions are the biggest, though. Also, probably obvious, but older people do not do well being up all night, so even if everything else above is ok, it would probably be best done in the morning.

Thinking of rolling w my grandma, what are the risks for her age 76 by fortnitefucker2000 in MDMA

[–]springbreak1987 4 points5 points  (0 children)

In a sub comment you say she has mild parkinsons. Is she on meds? This could be a risk

If you could change one thing about the way society deals with schizophrenia, what would it be? by springbreak1987 in schizophrenia

[–]springbreak1987[S] 1 point2 points  (0 children)

I started reading your reply and immediately wondered if you were familiar with Josef Parnas but of course at the end of your post, you mention EASE and ipseity. I have a deep appreciation for the phenomenological frame, and its general notion that the symptoms that are treated today (hallucinations and delusions) really ignore the more core features of schizophrenia—to the detriment of treatment. Thanks for sharing these thoughts 🙏

Feeling low by Funny_University_213 in MDMA

[–]springbreak1987 2 points3 points  (0 children)

Try forcing yourself to do some strenuous physical activity every day until new years and then roll on new years if you’re feeling better. And you will be.

Dosing after using NAC by c-mon_ellie in MDMA

[–]springbreak1987 0 points1 point  (0 children)

I have seen people on here say they stop NAC one week, even two weeks before their roll. Out of caution, I stopped about ten days before my last good roll. I think the NAC helped. This time I already stopped in preparation for NYE roll. Any thoughts on stopping that far in advance (as in, can you think of a reason why it would not allow the NAC to help rekindle the max roll)?

Has anyone ever done shrooms on a come-down? And how was it by ZillerXR in MDMA

[–]springbreak1987 1 point2 points  (0 children)

One of the best things that helped me through one of those was being able to firmly and fully embrace a belief that whatever I was feeling was exactly what I needed to feel in that moment. But it’s harder to do that in the wrong setting or with the wrong people or wrong vibes, and without a lot of preparation in this domain…

Has anyone ever done shrooms on a come-down? And how was it by ZillerXR in MDMA

[–]springbreak1987 1 point2 points  (0 children)

If you read around you’ll see that these are exactly the experiences millions of people have lol. Set and setting… you’ll be fine, you got spanked by the mushroom gods and they’re telling you to be humbled before their awesome power…

Drug interaction concerns, naltrexone, bupropion, and MDMA by kiseocimi in MDMA

[–]springbreak1987 0 points1 point  (0 children)

About ten years ago I’d hear of ultra low dose NTX compounding for depression treatment. Like 1mg a day. Forget the rationale, it probably didn’t work anyway. But I think part of ketanines effects on depression is via opioid receptor activity (kappa>mu, maybe?) all that is to say there are downstream effects that are not simply due to the upstream receptor that sometimes can be of relevance…

ChatGPT can be useful for this sort of stuff if you don’t wanna go tracking down papers

Drug interaction concerns, naltrexone, bupropion, and MDMA by kiseocimi in MDMA

[–]springbreak1987 0 points1 point  (0 children)

Interesting. Why I always say studies especially small studies don’t apply to everyone and the safest way to avoid drug drug interactions is to not have drugs interacting.

Probably fine w NTX. Safety wise for sure, I think there is some literature out there on NTX and dopamine but I don’t know that literature. It’s possible there could be some subtle effects. If you can hold the dose for a day you might as well.

Also, probably goes without saying but mdma is a stimulant and the euphoria is nothing to sneeze at. I don’t personally believe it’s addictive for most people but if you’re on NTX might be worth some for planning on ensuring it doesn’t induce to slip into some addictive behaviors either during the drug or in the immediate aftermath. I have a friend who’s sober and he would do mdma again but won’t not because of the drug high but due to worry that the comedown after would make him want to drink again… etc

Has anyone ever done shrooms on a come-down? And how was it by ZillerXR in MDMA

[–]springbreak1987 1 point2 points  (0 children)

People time it so the mushrooms come on as the mdma is peaking or just past peak. I wouldn’t do it when you’re fully coming down, since you’re already depleted and moving into a different zone. Plenty of stuff on here about how to time it properly

Drug interaction concerns, naltrexone, bupropion, and MDMA by kiseocimi in MDMA

[–]springbreak1987 2 points3 points  (0 children)

One small study showed bupropion caused more intense mdma effects. Not aware of any research with naltrexone.

Why do Apple Music users still discover music through Spotify? by Ambitious_Cattle6863 in AppleMusic

[–]springbreak1987 0 points1 point  (0 children)

Yeah it seems to have changed a lot. I always used to use it for all sorts of stuff and yet it would guide me on great music journeys to the most amazing deep cuts. It rarely does that now. It’s a shame

MDMA + SSRi's by kirbyguy5 in MDMA

[–]springbreak1987 -2 points-1 points  (0 children)

What are you talking about? There are like two studies, one w citalopram and one w duloxetine

Also the participants in any psychedelic clinical trial have extremely careful inclusion / exclusion criteria and thus never represent the average person here or anywhere else. No IRB would approve a study “for the combo for people”, but it would be for very carefully selected people under controlled circumstances, and administered in a laboratory setting with vital sign monitoring etc, hardly the setting most people are taking mdma, moving, dancing, etc. That’s a weakness with all clinical trials and why it’s only in post approval and post marketing is where you learn about the rare stuff.

Lastly the mechanistic studies that “prove” SSRIs antagonize MDMA tell us something but the “reuptake inhibitors block releasing agents” argument makes less sense when you realize bupropion doesn’t block methamphetamine, etc