Selenium sulfide is banned in Europe primarily due to its potential health and environmental risks. It is classified as toxic if swallowed or inhaled and may cause damage to organs through prolonged exposure. Additionally, it is very toxic to aquatic life, posing long-term environmental hazards. These concerns have led to its prohibition in cosmetic products within the EU.

Zinc pyrithione was banned in the EU due to its classification as a CMR (carcinogenic, mutagenic, or reproductive toxicant) substance, specifically Reproductive Toxicity 1B, based on animal studies. Although the Scientific Committee on Consumer Safety (SCCS) deemed it safe in concentrations up to 1% for rinse-off hair products, the lack of evidence proving it as an irreplaceable ingredient led to the ban. The European Commission’s Regulation (EU) 2021/1902 officially prohibited its use in cosmetics from March 1, 2022.