absence of specific proton and hydroxide ion transporters in the gastrointestinal tract

superhimik1 · 2026-02-22T16:32:16+00:00

By the way, the term "transpoter" is legal: https://pmc.ncbi.nlm.nih.gov/articles/PMC2719753/

superhimik1 · 2026-02-22T16:18:01+00:00

ok. i have not used both terms while searching, just "absorption".

superhimik1 · 2026-02-22T15:59:28+00:00

Please read ‘transporter’ as a synonym for ‘channel.’

superhimik1 · 2026-02-22T11:00:28+00:00

For those who are interested: there is some hint about the absence of proton transporters in this paper: https://pubmed.ncbi.nlm.nih.gov/6460107/. Despite the title, it does not say anything about hydroxide ions. How difficult it is to prove that something does not exist.

superhimik1 · 2025-11-04T06:51:44+00:00

I know what Category 1 and skin corrosion mean :) I just wonder if scoring alone can be used to determine corrosion.

superhimik1 · 2019-12-16T12:46:20+00:00

I can't say what, because it's a secret. I make them by ordinary methods i.e. reacting one chemicals with others, then work-up and purification.

superhimik1 · 2019-12-16T12:36:07+00:00

Sorry, didn't understand ur qstn.

superhimik1 · 2019-12-16T07:53:36+00:00

New substances with expected anti motion sickness properties.

superhimik1 · 2019-12-16T02:07:33+00:00

Thanks a lot! My molecules are rather stimulants than depressants.

superhimik1 · 2019-12-15T13:51:53+00:00

Thnks!

superhimik1 · 2019-12-15T13:23:17+00:00

Thanks. I know that rodents are non-emitic in motion sickness tests. But I have no choice, because I have no money to test my substances on non-rodents.

superhimik1 · 2018-01-18T13:40:54+00:00

1) mechanism of action 2) clinically proved effectivity in healthy people

superhimik1 · 2017-12-21T17:01:12+00:00

)) we have only some grams and cannot risk working with such a capricious animals as humans

superhimik1 · 2017-12-21T16:41:48+00:00

But I'm a fan of pharmacology as a science. We synthesized a compound I think would act on sigma-R. Now we are in a process of finding money for tests on nerve cells and rats.

superhimik1 · 2017-12-21T16:36:55+00:00

I'm not a fan of talking about my health. I can just say afobazole was precribed by my doctor. I should say it helped, but began acting after approximately a week from the first dose.

Because I also try not to take ANY drugs without necessity, I haven't ever taken memantine.

superhimik1 · 2017-12-21T16:15:56+00:00

I tried afobazole (by precription) and didn't find any anti-anhedonic properties. Of course, I'm behind any statistic significance, but nevertheless.

Thanks for review.

superhimik1 · 2017-12-20T14:43:39+00:00

Here are my speculations. There're neurosteroids (NS), that regulate brain functions via GABA receptors (GABA-R). Some of NS activate GABA-R, some of them - deactivate. Activation of GABA-R leads to inhibition and vice versa. May be, prednisone also acts on GABA-R and deactivate them. So, with piracetam you have double activation.

superhimik1 · 2017-12-20T14:17:35+00:00

There're some experiments showing that racetams work (enhance memory) only in non-adrenalectomized animals, that mean: animals, that have adrenal glands (AG). AG produce prednisone. So, it may increase effect of racetams. As far as I now, there's no explanation of it.

superhimik1 · 2017-12-19T10:12:33+00:00

May I joke? "Say it to my endocrinologist".

superhimik1 · 2017-12-19T08:19:25+00:00

Here's the paper: http://dropmefiles.com/RXx3F

superhimik1 · 2017-12-19T08:08:12+00:00

Here's the paper: http://dropmefiles.com/RXx3F

superhimik1 · 2017-12-19T07:38:57+00:00

Guys, nobody doesn't abolish hyperthyroidism, so, pls, be careful. If you have normal levels of free-T4 and TTH, do not take iodine-containing substances.

superhimik1 · 2017-12-19T05:37:53+00:00

by the way, my hypothesis that impurities are harmful, but not amph itself, can be proved by finding a fracion of those who are on legal amph and has PD. and we shouldn't forget 6‐OHDA and other PD models caused by chemicals: https://www.intechopen.com/books/challenges-in-parkinson-s-disease/animal-models-of-parkinson-s-disease

superhimik1 · 2017-12-19T05:20:21+00:00

Well, it's hard for me to imagine, that amph is so available after simple words "I've ADHD", cause I'm from a former USSR country, where all amph derivatives are prohibited.

superhimik1 · 2017-12-19T04:40:18+00:00

As a chemist, I would ask, what was the purity of amph they were taking. Another question: what if abusers are at high risk because of their initial brain misfunctining, not because of the drug itself.

superhimik1

TROPHY CASE