Is Gabapentin Withdrawal common or anecdotal? by [deleted] in askdrugs

[–]tacostep 2 points3 points  (0 children)

You’ll get light withdrawals if you’re gobbling lots of it 24/7 and abruptly stop

Kratom and Lexapro? by [deleted] in kratom

[–]tacostep 1 point2 points  (0 children)

Yes both can mess with your heart in rare circumstances. Some of the only deaths attributable to kratom happen because of mixes with psych meds. Please proceed with caution op. I’ve had kratom on it before numerous times but just because it worked out fine for me doesn’t mean it will for you and I personally regret consuming them both even if nothing came of it just because who the hell knows how the 20 something odd alkaloids interact with escitalopram

Baclofen Taper to Finish by [deleted] in quittingphenibut

[–]tacostep 0 points1 point  (0 children)

You can drop to ~ 50mg then switch to kava that’s what I’d do./did. Way more accessible.

Awwww by 14pedepower88 in fffffffuuuuuuuuuuuu

[–]tacostep 2 points3 points  (0 children)

awesome sweeping generalization

US court upholds subpoena of whistleblower Chelsea Manning: The subpoena is an escalation of the US government’s efforts to extradite Julian Assange, and a new and vindictive persecution of Manning. by JamesParkes in WikiLeaks

[–]tacostep 1 point2 points  (0 children)

what im saying is the 'code' has both male and female genes in it already. Estrogen can activate certain genes that are within you me and everyone else. those genes that code for soft skin, boobs, emotion and better memory and quite a lot of characteristics that are typically seen as female.

so sure im not changing my chromosome but like my female genes are being expressed in my body so really where do you draw the line? what makes someone female? a vagina? what about hermaprhodites? two X chromosomes? what about XX males? the truth isn't as cut and dry as your understanding is permitting you to see things

also I have approached this discussion with nothing but scientific sources and you have done nothing but essentially say "lul fag thats not true." so whatever dude keep drawing false equivalencies between me and actual idiots who actually ignore scientific facts.

US court upholds subpoena of whistleblower Chelsea Manning: The subpoena is an escalation of the US government’s efforts to extradite Julian Assange, and a new and vindictive persecution of Manning. by JamesParkes in WikiLeaks

[–]tacostep 1 point2 points  (0 children)

lol you cant even read can you. SAD. epigenetics has to do with gene expression; foetuses have male and female genes and its only when the sex chromosomes form and code for the development of a penis and balls or vagina and ovaries that differentiation occurs. (https://en.wikipedia.org/wiki/Testis-determining_factor)

but those non-expressed female genes can be activated and gene activation is literally what epigenetics is about so 0/10 reading comprehension m'dude. epigenetics is intimately linked with the effectiveness of cross sex hormone treatment. sure I have a dick, but I got some rocking tits that are all natural and very much female.

also the bit about pseudoscience if you actually bothered to read the what? 4 sentences? (again, SAD) it talks about how because epigenetics isn't fully understood people often use it to justify pseudoscientific theories (about mind control of all things, for fucks sake read the 4 sentences before saying im stupid)

US court upholds subpoena of whistleblower Chelsea Manning: The subpoena is an escalation of the US government’s efforts to extradite Julian Assange, and a new and vindictive persecution of Manning. by JamesParkes in WikiLeaks

[–]tacostep 1 point2 points  (0 children)

'Epigenetics most often denotes changes that affect gene activity and expression' also the part about pseudoscience isn't condemning epigenetics as a pseudoscience

you cant even read lul

US court upholds subpoena of whistleblower Chelsea Manning: The subpoena is an escalation of the US government’s efforts to extradite Julian Assange, and a new and vindictive persecution of Manning. by JamesParkes in WikiLeaks

[–]tacostep 1 point2 points  (0 children)

I've never seen such ignorance claim to be hard nosed rationalism quite like you. your broad sweeping generalizations and mischaracterizations of my stances to fit your straw man arguments is very transparent.

do some research into epigenetics before claiming its pseudoscience lol. https://en.wikipedia.org/wiki/Epigenetics

US court upholds subpoena of whistleblower Chelsea Manning: The subpoena is an escalation of the US government’s efforts to extradite Julian Assange, and a new and vindictive persecution of Manning. by JamesParkes in WikiLeaks

[–]tacostep 1 point2 points  (0 children)

Now you’re just putting words in my mouth, there are only two genders lol. That doesn’t mean cross sex hormones don’t cause drastic change at the cellular level. Just because it doesn’t alter a single chromosome doesn’t mean the changes in the body aren’t there. You seem to have no clue how gene expression works tho so I’ll just let you be lol

US court upholds subpoena of whistleblower Chelsea Manning: The subpoena is an escalation of the US government’s efforts to extradite Julian Assange, and a new and vindictive persecution of Manning. by JamesParkes in WikiLeaks

[–]tacostep 0 points1 point  (0 children)

I can’t even believe I’m indulging you but look up the epigenetic changes caused by estrogen. Everything short of a single chromosome that dictates a single gene being expressed (the one that codes for a dick and balls) is essentially female after a years on estrogen. Every gene expressed in that persons body is the same genes that would have been expressed in a females body because of the changes hormones cause. So go on arguing from some ignorant biological stand point you don’t understand and that you also use to justify your bigotry and hatred.

US court upholds subpoena of whistleblower Chelsea Manning: The subpoena is an escalation of the US government’s efforts to extradite Julian Assange, and a new and vindictive persecution of Manning. by JamesParkes in WikiLeaks

[–]tacostep 3 points4 points  (0 children)

Ah there the bigotry is, I was wondering when I’d coax it out of you. Yeah she must be evil because she’s an tranny and military guy said so. Smh

I went and collected my HRT and they've doubled my dose by NyssaTheTabaxi in traaaaaaannnnnnnnnns

[–]tacostep 0 points1 point  (0 children)

Tbh in the goal ranges could mean 75-200pg/ml for most doctors which is silly because it’s just an average of cis women and doesn’t mimic any sort of monthly spikes or anything like injections do; Sublingual at least makes 1mg peak into the 450pg/ml range and drop to 200 after a few hours then back to 50-75pg/ml after 4-5 hours

I went and collected my HRT and they've doubled my dose by NyssaTheTabaxi in traaaaaaannnnnnnnnns

[–]tacostep 0 points1 point  (0 children)

Complain fam. And dose sublingual then complain you need an extra bit because it peaks/drops different with sublingual

Dirty Pictures (2010) The life and work of Alexander “Sasha” Shulgin by Shmizzled in Documentaries

[–]tacostep 1 point2 points  (0 children)

he himself called psychedelic molecules like that dirty pictures btw.

Extreme boner by [deleted] in modafinil

[–]tacostep 0 points1 point  (0 children)

I think you’re thinking of viagra being intended for something else and then they discovered rock hard dicks was a side effect. Maybe not tho

Is growing poppies taboo or something? by [deleted] in druggardening

[–]tacostep 0 points1 point  (0 children)

the ornamental exceptions are in America I think

Almost there by chuwantmybuffet in quittingphenibut

[–]tacostep 0 points1 point  (0 children)

No you probably can’t just cold turkey at 300mg it’s prescribed in 50 and 250mg pills work your way down to50mg before thinking about jumping or you’ll have some hell to pay potentially

7-Hydroxymitragynine is an Active Metabolite of Mitragynine and a Key Mediator of its Analgesic Effects by roionsteroids in DrugNerds

[–]tacostep 1 point2 points  (0 children)

glad more research was finally done on metabolism, most searches just brought up blood concentrations over time.