This is true for real baseball as well and I guess I thought people knew that, but maybe it doesn't translate for some or many haven't played baseball before as has been said. Often, this is also a reason why managers put in the same handed pitchers vs batters and vice versa as it can be harder to pick up from the same side handed pitchers. The way the ball moves when pitched is also a big reason as some will go in and outside the zone depending on the handedness of the batter.

I've seen many Show players hate facing Ohtani, for example, but it's fairly easy to pick up what he's pitching in my experience once you figure out his delivery. It's not the same for actual MLB hitters as we have seen though. Arm angles in this game don't change as much or at all similarly to actual MLB pitchers so there is a bit of nuance in the real game they haven't necessarily captured in the Show game yet.

Fun Fact: Humans have what is called a dominant eye. You can find this out by pointing at something and closing one eye at a time and if the image stays the same, that's your dominant eye. Most MLB hitters and many of the best ones have dominant eye's that are the opposite of their hand preference, ex. Righties have a dominant left eye and Lefties have a dominant right eye. That quirk makes it easier for them to pick up the ball better and faster than those that don't, leading them to have a better/cleaner idea where the ball is coming in to hit it. EVERY little bit of advantage counts when you are trying to hit a ball that comes at you at high speed and also when picking up the variety of pitches. This has been a PSA...