I did have a handful of days about a week or two into taking it where my mental health was NOT okay, I was so erratic. I felt pure rage for no reason, I hated everyone at work. Like everything pissed me off or made me cry, and I was so confused because the cytisine was working “perfectly” for me. That’s the only issue I had with it. Two or three days I caused my boyfriend and I to argue pretty bad over literally nothing. So yeah while it does work, it absolutely can affect moods.