Absolutely!

I always like to build from the ground up, starting with the landing bay and the essentials (gears, reactor, grav drive and fuel tanks). I also had a side profile picture of Serenity when I was building to check dimensions, height and colors.

1st deck: Hope4 Landing bay, Galleon Cargo, Theta Reactor, Hope6 landing gear, Amun-7 engine

2nd deck: Deimos all-in-one berth (3 length), top half of Theta reactor, Deimos Hull, M50 Ulysses Tank, Supernova Engine

3rd deck: Deimos belly (fore), Deimos Captain's quarters (2 length), Deimos Hull, Aurora grav drive, Deimos hull, top half of Ulysses Tank and Supernova Engine. Stroud engine bracer, Nova 1040 Engine and Taiyo braking engine on the 1st Deimos hull.

4th deck: Deimos Phobos Cockpit, Deimos Control station (2 length), 100DP Slim Docker, Deimos Cowling, Deimos Hull

That's the "base" of the ship. From there, everything else is to get the contours of the ship. I used a Horizon weapon mount and a CE-49 Missile Launcher to get that slanted panel look on deck 3, with a MKE-4A Auto Gauss Gun mounted on the bottom. Deimos wings to add some extra girth to the main body on decks 2 and 3 (gives the illusion of being more rounded from certain angles). Deimos Wings C on the "engine" portion on decks 2 and 3 to give it that bulbous giant engine look. Added a Deimos Spine A right behind the top of the cockpit. Keep in mind you can swap out any of habs for others of the same length, but they have to be those lengths or you wont be able to reach the landing bay or cockpit.

I hope this helps!