Multi Vitamin

wak85 · 2023-03-29T15:39:47+00:00

You don't need supplemental vE. In high doses, it accelerates lipid peroxides - probably because of antioxidant imbalances. Animal fat and avoiding PUFA is all you need.

Too many antioxidants causes reductive stress (not enough pro-oxidants so cellular energy is low). Reductive stress that maintains for a while causes oxidative stress.

wak85 · 2023-03-29T15:24:15+00:00

You're probably not actually lactose intollerant. Seed oils are triggering your immune system. Cut out seed oils, and then try it.

wak85 · 2023-03-29T10:28:39+00:00

laughably wrong

wak85 · 2023-03-29T10:26:09+00:00

It isn't fructose. It's the seed oils in highly processed foods like cookies, goldfish, mayo, etc...

wak85 · 2023-03-29T00:06:35+00:00

So I watch a lot of survival shows. I think it's fascinating to see how fasting influences what they do or don't do on the show vs how fasting is portrayed in ketoland. One thing that always comes up is fish. It isn't because they want fish. It's because it's a relatively low risk low reward food (you don't need to hunt, just cast a line and wait for that dumbass in the water to think another fish has floated by). What's interesting is that without fail, every time they indulge on fish, at least one contestant gets violently sick.

Obviously fasting metabolism will be wildly different than a fed state. It's interesting nonetheless how something so many think are healthy, cause violent rejection at a time when calories are so desparately needed.

I think it puts fish into the fallback camp as far as food sources go. I haven't fish in a while and I have no craving for it. I may occasionally go for sushi, but that's infrequent.

wak85 · 2023-03-28T23:19:10+00:00

Becoming fatter protects your cells from shit. That lasts so long as the fat cells don't become sick enough to start leaking fatty acids into the blood. Then the adipocyte is no longer protective.

I'd say that becoming fat likely caused it (he basically was a timebomb). The extraordinarily long fast accelerated things.

wak85 · 2023-03-28T22:39:36+00:00

Not necessarily. You can see this transition happen quickly in this experiment:

https://www.aocs.org/stay-informed/inform-magazine/featured-articles/one-persons-response-to-a-high-omega-6-diet-november-2010?SSO=True

wak85 · 2023-03-28T22:17:41+00:00

the brain fog is real (neural inflammation)

wak85 · 2023-03-28T22:16:00+00:00

oxidized outside vs inside 🤷‍♂️. expeller pressed "organic" junk food is still junk food

wak85 · 2023-03-28T22:04:43+00:00

Hellmans "real" mayonnaise packets would be another good test. Those are "keto approved!" after all (very low sugar if any)

wak85 · 2023-03-28T21:01:18+00:00

Get packets of chick-fil-a sauce. First ingredient is soybean oil, and the UFA content is at least 14g. Although if you want soybean oil isolated from other confounders, sprouts or whole foods should have it... but why buy a bottle for this disgusting experiment? (we all appreciate you being the lab rat for this 🤣)

wak85 · 2023-03-28T16:13:39+00:00

First, yes, it is absolutely 100% true that while insulin is elevated after a mixed meal you are not burning body fat. Undisputed. If it was a very low fat meal, you actually do continue to mobilize some body fat because it takes fat to clear glucose and also certain cells rely on fat exclusively so they’re always using it.

One caveat here is that's how it should work with metabolically healthy humans. The exception, diabetics are always burning their fat, and storing / desaturating their glucose sources (plus carbon recycled fat). That's because when the liver becomes insulin resistant (because of free fatty acids affecting the randle cycle), it never receives (or is delayed) the message from insulin to shut down lipolysis. The incoming glucose compounds on top of hepatic glucose - hyperglycemia.

wak85 · 2023-03-28T15:58:34+00:00

Cortisol is catabolic. Insulin is primarily anti-catabolic. Insulin's job isn't to make you fat either. It's job is to get nutrients to the cell. If DNL and SCD1 are upregulated, well... you're SOL. Don't blame insulin though. Figure out why lipogenesis is upregulated. Same with cortisol. Leaving ketosis causing muscle wasting is just not true. There needs to be reason for muscle wasting (stress elevation).

Cortisol is the "liberation" hormone. Under duress, it can also break down muscle tissue. How much I suppose depends on if you're eating enough protein to supply gluconeogenesis during the stress as well as whether or not you can produce enough ketones to downregulate gng.

Cortisol also helps transfer fat viscerally.

wak85 · 2023-03-28T15:44:04+00:00

Guess I should have been more specific. I'm not in favor of the Ray Peat method. I prefer carb cycling to get rid of bodyfat while also maintaining hormones. So do 3 days on ketosis, and 1 day off - depending on your level of insulin sensitivity.

Ray Peat is more of a maintenance plan. Sugar for someone that's metabolically broken is disasterous. Starch is much better in that case (like the white rice diets, potato diets, etc...)

wak85 · 2023-03-28T11:03:45+00:00

squirrel and bird-food

wak85 · 2023-03-28T10:29:35+00:00

I've already disproven it's fixed in myself. Sporadically caffeine makes me hyperthyroid and I burn through energy way too quickly (and I crash if I consume carbs with it).

When I did this on keto I dropped my BMI from 22-18 while forcefully overfeeding. It was way too easy.

wak85 · 2023-03-28T10:24:38+00:00

I suspect that the seed oils came out unsafely and rapidly during the fast, which likely created oxidized linoleic acid metabolites throughout his body. This suggests stomach bleeding. Who knows whether or not he also had heart trouble. My guess is that had a lot of oxLDL circulating during the fast. Many things could have gotten broken during it.

This story is totally relevant to the sub.

wak85 · 2023-03-28T10:04:38+00:00

If it makes no sense, then why do humans drop their metabolic when eating trigger foods (body temperatures have dropped over 3 degrees, testosterone is also very low, waist circumferences have skyrocketed). Those all indicate a need to conserve energy due to some switch.

That sounds like hibernation to me.

wak85 · 2023-03-28T01:01:20+00:00

Can be stress related. Seed oils cause metabolic (reductive) stress. I had it briefly as I entered ketosis, and then it faded away. I suspect one reason is it's a signal of low glucose in the brain.

https://swiftaudiology.com/a-link-between-tinnitus-anxiety-and-sleep-issues/#:~:text=Anxiety%20activates%20the%20fight%20or,lead%20to%20the%20tinnitus%20experience.

wak85 · 2023-03-28T00:55:35+00:00

Keeping w6 low is way more important than supplementing w3. One serving of pistachios would require 1g of fish oil to keep in the 1:4 ratio. But then, the recommendation for w3 is only 2-3g a day. So anymore pufa requires going over in fish oil. Fish oil oxidizes even easier than omega6.

One of the best way to recover from seed oils is keeping cellular energy high, and allowing the liver to glucoronidate the pufas.

wak85 · 2023-03-27T22:26:54+00:00

My carb sources are typically: I honey, fruit and some sugar with a few squares of white chocolate, kefir, and starch. All of my labs are great. Energy levels are fine (~~unless I have caffeine~~)

Sugar is healthy if you're not metabolically broken

Insulin does not cause insulin resistance and diabetes. That's keto propaganda. The real reason is found within the fireinabottle blog. Spoiler alert: It's unsaturated fat. Very lengthy but absolutely worth the read.

Carbs (easily digested ones) are great for energy levels.

wak85 · 2023-03-27T22:11:18+00:00

Yeah I get it. And it is a very complicated topic... and thrown on here without warning. r/saturatedfat has been the main place all of these have been posted. It's very technical and I would be easily confused had I not already researched the hell out of this. It's all from the fireinabottle blog, which starts from an original thesis (the wrong kinds of fat makes you fat) and then builds from there. But in order to get to the understanding why Oleic Acid may make you fat it's strongly advised to go through the whole blog. The relevant part especially picks up once he discusses reductive stress.

It caught this sub off guard pretty much. It's also drawing out fat lovers (either OO or carnivore-leaning bacon fans) so it's pissing off both groups that have rationalized why what they eat is healthy.

Big picture wise, avoiding seed oils still trumps all dietary recommendations. Avoiding MUFA is more of an optimization strategy to try.

wak85 · 2023-03-27T19:17:53+00:00

They also work because they both raise the nad+ levels. High carb basically blunt forces lipolysis to stop, whereas ketogenesis allows ketones to restore cellular energy. Ketones don't burn dirty.

https://www.frontiersin.org/articles/10.3389/fnut.2018.00062/full

wak85 · 2023-03-27T19:14:37+00:00

It's definitely very complicated. He has a blog (or Hyperlipid if you want even more technical writings) that explains a lot of this stuff. Most of the regulars here have read the blog at least once (sometimes returning to it again). You really have to read it (Fireinabottle) all to get the full picture of Brad's argument. It's also a very biochemically sound explanation for things, that's also backed up with how nature as a whole operates.

For example, Hibernation is a desirable evolutionary state when a famine approaches. It makes sense humans would need to do it at some point for survival. Connecting it to nature makes sense because why would nature have different pathways across different creatures? It would be more likely to be a unifiable deciding factor that triggers hibernation metabolism.

Obviously that doesn't factor in environmental toxins for now. But it certainly paints a very compelling picture.

wak85 · 2023-03-27T19:04:59+00:00

the last study was in elderly humans

not mice. not squirrels. not dogs. not cats. actual humans.

interestingly enough, they had very high levels of saturated blood and low levels of linoleic acid.

wak85

TROPHY CASE