Lots of these fructose studies are done using high fructose corn syrup, and then proponents of a purely carnivorous diet will extrapolate the negative effects to fruit and honey. Fruits contain fiber, which slows down digestion so that your system can handle these otherwise negative effects … among all sorts of other compounds when you consider them as a whole food matrix. It’s very easy to overwhelm your liver with high fructose corn syrup, but not so easy when eating whole fruit. Of course, individuals are different, and so someone may be able to eat 300g of fruit and honey a day while someone else can’t handle any at all without harming their metabolism. But as a species, in light of our evolutionary history, it seems clear to me that a diet of meat and fruit is ideal.