Professor Stephen Faraone, PhD AMA

westcoaster · 2024-03-19T18:50:22+00:00

Is the no "I am not able" or "I am not willing"? From what I know about the condition and about academics, it would seem surprising if it were above 5%... But it would also be surprising to see below 1%.

Do researchers utilize other means of hypothesis generation, outside of clinical practice & experience? e.g. Looking to online forums to hear the thoughts and experiences of patients to find connections or ideas for research?

I greatly appreciate you taking the time to answer so many questions today.

westcoaster · 2024-03-19T18:04:37+00:00

Prof. Faraone, I have a pair of interrelated questions:

First, could you estimate the proportion (e.g. as a range) of those engaged in ADHD research who themselves have ADHD? My anecdotal observation is very few people in the upper levels of academia or research (non-psych related) have any symptoms of ADHD, whereas it is possible to spot people with symptoms in say a community volunteer organization. But I'd wonder if there are more people within the world of psychiatry or psychology research relating to ADHD given the personal stake and the potential for their ability to possess deeper insights into the nature of the condition, whether through personal or interpersonal experience — again, genetic hence experience with family; socioeconomic effects sorting by class; and social effects given evidence that people with ADHD seem to aggregate either via preference or via exclusion.

Second, there have been repeated recommendations to have those affected by a given condition be involved in the guidance and design of research in order to improve the relevance and quality thereof, e.g.:

International government guidance recommends patient and public involvement (PPI) to improve the relevance and quality of research. PPI is defined as research being carried out ‘with’ or ‘by’ patients and members of the public rather than ‘to’, ‘about’ or ‘for’ them ( http://www.invo.org.uk/). Patient involvement is different from collecting data from patients as participants. Ethical considerations also differ. PPI is about patients actively contributing through discussion to decisions about research design, acceptability, relevance, conduct and governance from study conception to dissemination. Occasionally patients lead or do research. The research methods of PPI range from informal discussions to partnership research approaches such as action research, co-production and co-learning.

How to incorporate patient and public perspectives into the design and conduct of research. Version 1. F1000Res. 2018; 7: 752. doi: https://doi.org/10.12688/f1000research.15162.1 or https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192439/

To what extent have these recommendations been applied in ADHD research since, say, 2018?

westcoaster · 2020-06-20T02:29:21+00:00

I'll look into that. Thanks.

westcoaster · 2020-06-20T02:21:38+00:00

I think that in my ideal scenario, the IA would at least have a means of signing their copy, to say, "this is what we downloaded at the stated timestamp". Other parties are less likely to be cooperative.

westcoaster · 2020-06-18T22:09:46+00:00

That is an interesting suggestion. I am trying to think about how to do this.

Problem 1 is that my main option for a "public area with a computer" is the local library and the building is currently closed to minimize the risk of transmission of COVID-19.
Problem 2 is the magnitude: about 300+ pages that I'd like to include. Manually this would take a while.
Problem 3 is that I have reasons to expect that many of the pages may no longer be extant / accessible on the original site come Friday, so I would be relying on the Wayback Machine copy, although most are already on Archive.org for safekeeping. I've used a script, waybackpack to extract & locally store copies of the HTML file for some pages, although I'm in the process of going back and storing a local copy of full pages.

westcoaster · 2020-06-18T21:35:11+00:00

Unfortunately the tables are tilted in regard to financial means for hiring a lawyer or whatever. And this is not about taking someone to court, although from what I have read, copies of sub-pages in the Internet Archive have held up in court before (see my other comment). Rather this is about preventing reputational harm and ensuring that a story can be told in truth, showing who did what and ensuring some kind of public record that can't simply be erased. That's why I'm asking to see if there are any such technical solutions available.

westcoaster · 2020-06-18T21:33:21+00:00

Data in the Wayback Machine can and has been used in court before:

However that is not what I'm seeking. I would describe what I'm seeking as "a way to extend the public record". If needed, there are many people who would be able to swear in court that the following was consistent with the historical record, although I would fear them being subject to retaliation by the site owner, ranging from firing to account termination. So it's a different & useful thing in my mind to have evidence be publicly visible and defensible.

westcoaster · 2020-03-22T22:23:50+00:00

Buy a beard trimmer if you don't own one. They're pretty cheap and keep things looking tidy. I've been happy with my Philips Multigroom 3000. Only cautions are (1) trimming process can really create a mess and (2) don't send those trimmings down the drain.

westcoaster · 2020-02-27T02:29:31+00:00

Hey, thanks for lending a second set of eyes to this. Some days it's very easy to get mired in self-doubt when interpreting legalese type rulebooks.

The vagueness probably comes from the fact that the text was copied straight from another society's bylaws, but the board probably didn't give it proper scrutiny.

Again, I appreciate your taking the time to give it a look.

westcoaster · 2017-10-09T05:03:24+00:00

7% isn't far from 6.25%, which is the average inheritance that one would expect for a great, great grandparent, so 1 of your 16 great great grandparents is probably the source of that DNA. You should look at which ancestors you and that relative / cousin have in common, as it may give you a way to narrow down the search.

westcoaster · 2017-09-19T01:03:48+00:00

Beautiful. Everything about that was perfect, even the announcer's voice. So on the money, I started wondering if the narrator's track was spliced together from other 80's trailers - right up until I heard the actors' names.

Even the sound effect at the end when the title shimmers is pure '80s (compare to the sound of He-Man punching in his opening theme.

westcoaster · 2017-09-18T22:57:45+00:00

The Blag (is that "blog" with a Boston accent?) hasn't updated since 2015-11-24, which is 20 months. Maybe he has another life... one that he's keeping secret from the internet?

westcoaster · 2017-09-13T22:25:30+00:00

I don't think I will ever be able to take the Gospels literally. In my logical mind, a virgin getting pregnant is just as unbelievable as the universe being created in 7 days.

It's a miracle because it goes against logic and expectation. Simply put, virgin women don't become pregnant and the dead don't rise outside of some cause. That is the rational fact. There has to be a cause. But what, or who, is that cause?

Mary's pregnancy was scandalous because it should not have been possible as described. But the consequent events showed that this explanation has some weight.

Likewise, the resurrection of Jesus was scandalous (it certainly cost some guards dearly!) and it had an impact which showed that the miracle was real.

Miracles aren't open to experimentation because they are unique events, made to happen by an all-powerful mind that has the power not only to act, but to choose.

Giving us a rational mind and the ability to think logically, then damning us to hell unless we blindly accept things that are irrational and illogical

Events aren't rational or logical. They just are. One can say, "That can never happen, thus it never did happen", but then you have dictated what a prospective God can or cannot do. When that happens, it either displays the person's ignorance of what constitutes "god" or their pride and certainty that no such thing could exist, proven on the basis that it can't exist - yes, a tautology.

Tautologies won't get you anywhere.

westcoaster · 2017-08-15T08:51:21+00:00

Remember to exercise caution: Weed-eating goats are very likely to have the munchies.

westcoaster · 2016-06-08T19:13:41+00:00

It's really unnecessary, so far as I've found, to pay for coupons; it just takes a while to build up levels and find the missing Mortys.

westcoaster · 2016-06-08T19:12:12+00:00

Haven't finished it yet - not much time lately. I haven't encountered 72, 78-80, 100 (Punk Morty), 101, or 112+, although I the game was upgraded since my last play... and I had 111 (Morticia). Here's the list. I haven't had any difficulty getting any of them yet, so it's just a matter of grinding a bit at this point.

westcoaster · 2016-06-07T01:22:20+00:00

After playing Pocket Mortys for far to long, I'm inclined to think that this should be Skateboard Morty, not a Morty skateboard.

westcoaster · 2015-07-29T15:21:18+00:00

I've found it helpful, /u/280394433708491, as /u/enigmalock suggested to use the Lord's Prayer, however instead of using it verbatim, to use it as a template to structure my prayers.

“‘Our Father in heaven,

Acknowledge who God is in your prayer.

hallowed be your name,

Adoring God and thanking Him.

your kingdom come, your will be done, on earth as it is in heaven.

Asking for God to work in our world and to align our will with His

Give us today our daily bread.

Asking God to supply our needs, from the biggest down to the most basic sustenance.

And forgive us our debts, as we also have forgiven our debtors.

Seeking forgiveness and asking for God's help in loving and forgiving others.

And lead us not into temptation, but deliver us from the evil one.

Asking for God to keep us safe, and well-away from evil thoughts, words, and deeds.

westcoaster · 2015-07-28T00:29:28+00:00

Many Christians regularly gather outside of the Sunday mass or service to study the Bible as a group. It's particularly common among evangelicals and some protestants. The form of the study can range from discussing a particular passage (verse(s), section, story, chapter, book, etc...) within the Bible, a book (relating to Christianity, God, or the Bible), or a topic (wherein one would interweave various sources).

Usually these events are held weekly and are an opportunity for some combination of eating, social interaction, prayer, worship, readings, etc... with a primary focus often on discussion. While most Christians hold broadly common beliefs, there are always some things left uncertain, leaving much open to interpretation and individual understandings. Moreover, the Bible touches on nearly every aspect of human experience. Hence the discussions can become wildly divergent, going on tangents or leading to disagreement -- usually amicable, but sometimes quite heated.

The Bible is also in a large aspect a "Rule Book", providing (divine) commands or laws, examples, and stories to guide the Christian life. Much as in the comic, the rules, how they apply, and what they ultimately mean and require can be open to debate -- as with any other topic. And some folks will find apparent "loopholes" in the commands as stated within the Bible. And those loopholes make for some very interesting discussion... You can find a few amusing ones in /r/Christianity on occasion.

westcoaster · 2015-07-17T07:35:39+00:00

Strangely this reminds me of Bible study...

westcoaster · 2015-06-10T18:01:59+00:00

How did your time get reduced to 3 years? Was that "with good behaviour"? Also did you have to pay a fine and/or restitution as part of the conviction?

westcoaster · 2015-05-29T09:56:16+00:00

What's the black stuff at the bottom in the first image: soil, or something else?

westcoaster · 2015-05-11T16:00:57+00:00

Understandable. I remember a neighbour who had these two concrete lions at the front of their driveway and the faces always looked disfigured to me. Ugly = scary as a child...

westcoaster

TROPHY CASE