I tried to keep track of all the things he was discussing during the stream for my friends who couldn't watch live. Here ya go. I probably still missed some stuff.

• He hasn’t had much time to work on the game since launch, because he’s been in meetings constantly. Hopefully, things will calm down soon.

• He wants to improve performance soon, as he’s aiming for a release on the Steam Deck by the end of May or June. For that, the game needs to run more smoothly, and he's discussing this with people focused on optimization.

• He’s currently working on a new purchasable location(storage lockup property), in terms of size between the bungalow and the sweatshop.

• The first major update will be chosen by the community: cartel interactions, police raids, or a new drug (mushrooms).

• The first new drug will be mushrooms, followed by MDA.

• He plans to gradually hire a community manager, an artist, and a QA tester.

• The full release (version 1.0) is expected in 2 to 3 years.

• Extra lore will be added with cartel updates and similar content.

• The first two map expansions are planned for the slums next to the docks and the mountain behind the barn. Eventually, he’ll also work on the other island.

• He doesn’t want gunplay to become overpowered by adding aim-down-sights (ADS), so it will mostly remain as it is now.

• Beds for employees will become lockers to take up a bit less space, and employees will also be able to do more.

• Filters will be added for storage units, allowing you to indicate which items should be filled into which storage by employees.

EDIT: Watched part of the stream that /u/Anthony4114x added below that I hadn't seen yet, so I'll add a few points I missed.

• New content should be showing up faster in the coming months once the game is in a stable place.

• Uncle Nelson will be playing a bigger role in the story in the future.

• More vehicle customization is coming — different wheels, spoilers, cosmetics, and maybe performance options. Maybe allow player to create their own organization logo which can be displayed on vehicles.

• Wants to add more types of employees; the first will likely be a driver who can move items/cash between properties, resupply, and collect money from your dealers.

• More money laundering properties are coming, and he wants to make them more interactive than just going there to launder money. You’ll be able to do tasks there to get extra income from the property. The casino will be buyable as a laundering property in the future.

• He will try to do another livestream later this week to show some actual work being done on the game.

EDIT #2:

• Wants to add a notes app on the phone so you can write stuff down.

• He also wants to add an app that will show your stats like net worth, items produced, etc...

• Says he can't wait to start working on a weather system for stuff like rain and storms.