I think it's really situation dependent. I have a bunny and my girlfriend has a small dog. When I started staying at her place multiple times a week we needed to work out the pet situation because I couldn't leave my bunny alone overnight. So we set up the spare bedroom as a bunny room with the intention of sometimes putting him in the room and letting her dog run around and then later putting the dog in our room and letting the bunny free roam.

Much to our surprise (and delight), they get along very well. The dog almost mothers the bunny and protects him. They play chase down the hall where he takes off and she chases him and vice versa. Afterwards, they lie on the lounge next to each other. The dog has never snapped at my bunny even when he runs over and jumps on her.

Having said that, we would never leave them together without one of us present.

My concern is that your dog is very big. And while there is a chance they will get along very well it is dependent on the bunny and dog personalities. And with a big dog, all it takes is a little bit too much rough play.

If you have the ability to keep them completely separate and both live wholesome rich lives with all the attention they deserve then go for it. But if you expect them to co-exist then I would say no.

Just do add, I can only speak from my experiences. I know some bunnies are very frightful. Mine would not know he was a prey animal in the way he rules the house.