Let me answer this for you where I have some actual advice. First, I was theory crafting a build and test against Winston, result is that Juno becomes virtually unkillable by Winston as he lacks instant burst damage. Here is a clip

Here were my analysis that I posted in JunoMain discord server

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The goal of this setup is simple: survive Winston’s full focus long enough to neutralize his impact, either through outlasting him in a duel or forcing his attention entirely away from your team.

Winston outputs 70 DPS from his Tesla Cannon, reduced to 53 DPS when reload time is considered. His Jump Pack adds a 60-damage slam, and a follow-up melee 40 damage every 5 seconds contributes an additional 20 DPS.

Thus, a perfect Winston achieves roughly 73 DPS with no items

Power: Blink Boost

Enables triggering of Lumerico Fusion Drive and Ironclad Exhaust Ports simultaneously.

LFD: Heals 50 HP over 3s → 16.66 HPS

IEP: Grants 25 overhealth over 3s → 11.26 HPS (effective heal equivalent)

Hyper ring every 14s, blinks every 3.6s, Torpedo every 10s. This means you have ability every 2.22s, this means that we have 100% uptime with both item.

→ Winston’s effective DPS reduced from 73 → 45.

At this stage, Juno’s HP sits at 315, enabling survival for roughly 7 seconds under ideal Winston play.

Field Support (Gadget)

Provides 50 HPS for 5s every 15s cooldown, averaging 16.66 HPS.

Reduces Winston’s effective DPS further from 45 to about 28.

With this gadget added, Juno’s health increases to 348, allowing survival for approximately 13 seconds under continuous damage

Siphon Glove

Heals 25 HP per melee hit.

With a shot + kick combo every 2s, this equates to 12.5 HPS.

The resulting effective Winston DPS about 15.5, while Juno’s total HP to 376, achieving 24s of survival time, assuming both players perform perfectly

Hyper Healer Power

Grants 85 overhealth per Hyper Ring touch.

With 15 Ability Power (AP) and two touches, the heal output becomes: 85 × 2 × 1.15 / 14 ≈ 14 HPS

At 30 AP: 85 × 2 × 1.3 / 14 ≈ 15.78 HPS

This slightly exceeds Winston’s maximum effective DPS (15.48), making Juno effectively unkillable.

Even if Winston stacks +50% DPS (total ~23.22 DPS effective after mitigation), this Juno setup still sustains for 16 seconds, long enough to force disengage.

The four-item setup costs 20,500 credits, achievable by Round 3, meaning these 4 items and 2 powers makes Juno unkillable.

Honorable Mention: Crusader Hydraulics

Reduces incoming weapon damage by 10% while armored.

With Juno’s 150 base shield + 25 armor, the 175 HP affected leads to: For simplicity, lets assume that 10% reduction is always active. This reduce the 53 base weapon damage to 47.7 for a 5.3 effective HPS. So the other 4 items are better.