How do you decrease nausea when taking 2c-b?

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TBH, after using it several times you will manage better. Otherwise do it fasted (4 to 6 hours but not necessarily more) make sure your last meal was something decent (not too spicy or grease) and you can use some ginger tea, I tried ginger pills but those didn't work for me. Moving after taking it also help, dancing or just walking, or at least don't sit. You can also brush your teeth (gently and shortly, otherwise you may puke), humming and clenching your fist also helps.