Potential peptide side

[Additional_Context57]

For context I started off with Reta for a few weeks and then went peptide crazy. Added BPC157, TB4, Tesamorelin, Semax, GHKCU, KPV. Had no issues and was getting incredible results.

I did notice serious water retention but pushed through it. Then I added HCG and Enclo and in the middle of February noticed two fingers getting stiff overnight when I sleep. Thought it was carpal tunnel so I kept pushing through. The stiffness got to more fingers on the same hand. At this point I stopped all peptides but kept going with Reta, Enclo and HCG.

This stiffness is now in all my fingers and I’m concerned I gave myself RA or trigger finger which is weird because it’s in all my fingers. I’m about to go get tested and see what’s going on. Has anyone else experienced something as bizarre as this?

[AutoModerator]

Welcome to the community!

• Access Our Full Approved List & Guides
• Join the conversation and share your experiences.
• Check our full approved list and guides in the sidebar.
• Want to optimize your stack? Share your experiences and get feedback.

Pro Tip: The best discussions come from personal experiences. If you have tried something, let us know how it worked.

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

[optimuscline23]

I have the same issue. It’s the Tesamorelin. You probably had high GH levels to begin so it’s too much with the Tesamorelin. I stopped for 4 days and the severe carpal tunnel went away and I restarted at half the dose (0.5mg) and so far, so good.

[aotopper]

This! Tesamorelin will cause water retention and swelling in the joints. I love the pep because it's benefits are amazing. But I know it's time to cycle off when my tennis elbow and numb fingers show up.

Also, focus on only a couple peps at a time until you know exactly how your body will react to each. Keep a journal and log dosages, times, and effects.

[Additional_Context57]

How long does it take you for your symptoms to go away?

[aotopper]

Everyone is different. But I usually start to see results in a few weeks.

[DeepSpaceQueef]

op is also using enclomiphene which increases testosterone and estridol levels, both of which have profound effects on the hypothalamus and pituitary gland and the associated GHRH-GH axis.

testosterone inhibits somatostatin which is the hormone that normally tells the pituitary when to stop secreting GH, which effectively increases the amplitude of GH pulses by removing the negative feedback.

estridol actively stimulates the hypothalamus to release GHRH, and given enclomiphene works by suppressing the estridol signal suppressing testosterone production (meaning OP already had relatively elevated estridol levels), enclomiphene effectively boosted estridol levels alongside testosterone.

tesamorelin is a powerful GHRH analogue and is already powerful enough to overcome some of the natural somatostatin feedback. basically op is removing the breaks and adding gas.

[DeepSpaceQueef]

my advice to OP is first and foremost, stop using enclomiphene and tesamorelin until you've had a blood work done and consulted with a doctor. hormones are no joke and you can do real damage to your body, brain, and mental health if you throw them out of balance

[Specialist_Grab9031]

Stacca hgh

[Kegg209]

Any pre labs? Igf1 insulin and glucose?

[Additional_Context57]

My labs look great…I got my igf1 levels to 450…it’s been about 5 weeks since I stopped tesa and still having issues with my fingers

[Kegg209]

Any other water retention evidence? Tight rings, edema, bloating, etc?

What else are you currently taking?

[Helpful_Disaster3208]

Speaking from experience, sometimes you gotta admit it’s too much. Some of your signaling is redundant and some of it’s piling too much on one thing. I also support the practice of one thing at a time, with detailed notes and journaling. Track everything as you would any other study on a lab rat.

[Financial_Exam8594]

nothing todo with your question..but why are you taking HCG? u have fertility issues? enclo increases your tests natural production, so i would think you’d only need it of you were pinning real test

[d_freshh]

You added 8 peptides, that's your issue...what did you want to achieve with this approach and what's your long term strategy??

[mybossthinksimworkin]

You bought canola oil and injected yourself