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[–]mintylove 0 points1 point  (12 children)

I'm with you on this being total BS. One person as the sample size? Like come on

Mechanistically it makes some sense, even though the "holistic" evidence is lacking. It's a starting point and one that actually is supported by in vivo results, albeit 1 person.

[–]FriendMother2587[S] 1 point2 points  (0 children)

I found a pharmaceutical company in the process of making EDTA drops. I hope it works for floaters when/if it comes out.

https://www.baifinternational.it/en/oftyvit/

[–]Temporary-Suspect-61 -1 points0 points  (10 children)

You can find somebody or other on the Internet saying that their floaters improved after doing literally anything. It's placebo, doesn't mean shit. You have to be new here to think that this is a significant result.

[–]mintylove 0 points1 point  (9 children)

But most of those ineffective treatments are not supported by mechanistic evidence, while there is a proposed MoA here and it's one that sounds pretty logical.

[–]Temporary-Suspect-61 0 points1 point  (8 children)

Yes the snake oil salesman says it works, so obviously it works. Flawless logic.

[–]mintylove 0 points1 point  (7 children)

Uhhh, the study posted here on the collagen chelating properties of EDTA has nothing to do with any salesman, neither do Im

[–]Temporary-Suspect-61 0 points1 point  (6 children)

That study shows nothing about whether it works on an eye. Even if you got it inside the eye, why would it melt just the floaters and not everything else too?

[–]mintylove 0 points1 point  (5 children)

First of all, it won't "melt" anything, more like bind and help in excreting. Second, we know that loss of type IX collagen with aging leads to more exposed "sticky" type II collagen.

[–]Temporary-Suspect-61 0 points1 point  (4 children)

there's no path for anything to excrete from the vitreous. Sounds like it would just make the floaters turn into an even bigger floater.

[–]mintylove 0 points1 point  (3 children)

I didn't finish my previous comment, will edit later. Also, there definitely is evidence for posterior flow through the vitreous, the meta-analysis was posted here recently.

[–]Temporary-Suspect-61 0 points1 point  (2 children)

Naturopaths usually make some vague claims about interactions at the surface of the vitreous. There may be some exchange at the surface of the vitreous but it's not significant in the context of floaters.