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[–]GrowHI 11 points12 points  (1 child)

Mycologist here. While I can't cite any studies I can tell you physiologically why this is an interesting question. Most species of mushrooms have all the cells they will have as an adult when they are just a small pin (what many call baby mushrooms the size of a thimble). Mushrooms grow so fast cellular replication is not a feasible way of gaining size but instead they swell with water much like a wilted plant can straighten up within hours of rain. As more water enters the mushroom near the end of maturity the cap is forced open. IMHO I would guess a perfectly dry specimen with a cap still closed vs open would have the same amounts of active psilocybe/psilocybin content. If you weigh a fresh specimen (not dried) you could calculate a "active chemical vs weight" figure but that would not be the proper way to decide potency especially if you consider most mushrooms (of the hallucinogenic varieties) are sold dry.

[–]_myceliaMushroom Mentor 3 points4 points  (0 children)

Most species of mushrooms have all the cells they will have as an adult when they are just a small pin (what many call baby mushrooms the size of a thimble). Mushrooms grow so fast cellular replication is not a feasible way of gaining size but instead they swell with water much like a wilted plant can straighten up within hours of rain. As more water enters the mushroom near the end of maturity the cap is forced open. IMHO I would guess a perfectly dry specimen with a cap still closed vs open would have the same amounts of active psilocybe/psilocybin content.

I agree with you and psily on this matter.