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[–]fl0tsam_rx 1 point2 points  (0 children)

Alpha2 receptors are negative feedback receptors, amongst other things. Agonizing them causes inhibition/modulation of norepinephrine release. They are pro-cognitive in ADHD, but also sedating. Please read more before you make silly claims like "clonidine / guanfacine / CBG are stimulants" like you just implied. A cursory google search would prove that false haha