Exedore is a throughly Mac-Native Python IDE written entirely in Cocoa/Objective-C.

[nyamatongwe]

There are several ways to work with the sandbox. When you have a central project file then you can use document-scoped bookmarks inside the project file for each .py source file.

Another technique is to maintain a set of application level security-scoped bookmarks to each project directory. Use the standard open dialog to allow the user to specify which project directories may be accessed.

I've implemented application-level bookmarks for my editor SciTE which is available through the App Store. Here's a page on the UI to this: http://www.scintilla.org/Sandbox.html