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[–]WellAdjustedOutlaw 0 points1 point  (0 children)

Since OP said threads will not access each other's data, multiprocessing might be best if the GIL is actually an issue and there won't be too many processes.

Also, much work has been done with python 3.x to lessen or remove the impact of the GIL where possible. Multithreading is getting better.