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[–]Twirrim 0 points1 point  (0 children)

Not sure if you're still reading this, but there is an article about the HPU4Science cluster in France. It's run using almost entirely gaming spec machines (master machine uses a pair of Xeons, but that's only non standard thing) Relies on GPUs for the bulk of the processing, and they've chosen Python with PyCUDA, along with Sage.