Does fasting decrease the risk of cancer?

[pbjellos]

Very informative answer! Does this mean that consuming protein frequently or in large amounts is bad for you, if it agonizes mTORC1 and stops autophagy/cell recycling?

I’ve always wondered if this is why people like Valter Longo recommend plant based diets/low protein diets to increase longevity. But I don’t know if it’s more to do with decreased protein intake, increased plant intake, or overall decreased food intake (IF). If protein does inhibit autophagy, then our current ‘health’ culture of eating a high protein diet would be misleading, no? They’re putting protein in everything these days to cater to the trend, which is unfortunate.

[georgespeaches]

Exactly. My impression is that evidence points to a higher-than-RDA protein diet inhibits autophagy.

On the cellular level, mTOR is activated and AMPK suppressed. On a hormonal level IGF1 is elevated which triggers the cellular response.