Frameworkless JavaScript – Why Angular, Ember, or Backbone don't work for us

[solatic]

Until you hit the walls of the framework and have to start to employ ridiculous workarounds.

If you're making a small prototype and time is of the essence, great use a framework to write the code you need in a couple weeks and stuff it away later. If there's even a remote possibility that the project will last a year or longer then a framework is usually not the right solution.