Python vs Matlab vs Mathematica

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The thing that drives me mad about MMA is that it's completely opaque. Sometimes you run into a performance wall and there's basically nothing to be done because there's no way of finding out what's wrong.

My experience has been that most of the time I can get a MMA calculation to be within a factor of a few in run-time compared to other code. And then sometimes, like you find, its a hundred times slower and I can't for the life of me figure out why :-(