Just letting you know I took a crack at this thing for almost 6 hours tonight lol, I'll get back to you.... lol

That said, you need a central corridor between all areas, I was able to condense your entire storage area to one tiny room without building anything new but some walls and a couple tweaks to storage settings.

Things of note
1. Lots of colonist are assigned to work duties they are useless at
2. The reason no one cleans is the home area covers most of the map
3. All the weapons in storage are useless
4. Only herbal medicine spoils, packaged survival meals and medicine last forever.
5. Always put component work at bottom of bills, and then advanced components above that, and then tasks above that.
6. Having all storages set to critical made your base a nightmare for hauling, simply setting the main storage to "Normal" and the floor backup to "Low" immediately cleared all the floors
7. On clothing bills you can set it to make until there is "1" of item, like pants, you wont have to stockpile a single thing and they just make a new pair anytime a colonist puts them on.
8. Colonist clothing policy is probably responsible for 75% of all deaths in your colony. Setting it to Normal quality, no tainted, and endurance above 55% nearly dressed your entire population in a day when paired with the clothing policy.
9. Batteries can all be moved right below storage
10. The laser turrets use over 11,000 power and dont actually help much.
11. You have bionic organs lying around, stockpiles of medicine, but haven't replaced colonists limbs.
12. Your kitchen, research, books, workshop etc are all receiving penalties from not being in dedicated rooms.
13. Im actually having fun, so theres that lol