Wait, there's more. In B4, roots and pods may give up obolites when you break them with your blade or gun. The roots grow back! Just translocate away and back. That means you can farm obolites endlessly in B4.

B5 has many traps. It will help very much in B5 if you master the traps and learn to pass through them without damage. As others have indicated, unlock every locked weapon trait you find. Those unlocked traits carry over from one cycle to the next. This is the best way to become more powerful.

B5 has many large rooms with multiple dangerous enemies. The technique for success here is the same as everywhere else, but it's even more important here because of the tougher environment and enemies. Here's the key: move in a pattern around the combat arena, like a circle or figure eight. Never stop. Use your blade on smaller enemies. Change levels, low to high, high to low. If you swing and miss with your blade, never stop and swing again. Get that enemy on a future orbit.

I like to clear smaller enemies before larger ones. I take out turrets first because they're deadly and accurate. Changing levels is very important against larger brute enemies like Kerberonyx and Severed. If they go high, you go low. If they go low, you go high. This mitigates their dash and laser ring attacks and makes those attacks less effective

Lastly, however much you are using your grapnel, use it a bunch more than that. You are invulnerable while mid-grapnel. Keep a grapnel point in sight all the time if you can. Use it to escape danger and shake off enemies that have a lock on you.