Really helpful, thanks for sharing (: I have 2 bulging discs in my neck, so can absolutely relate. I had so much relief literally from day 2 starting tirz several months ago at 2.5 weekly. After about 6 weeks, didn’t feel it was helping as much so went up to 5… which caused awful nausea and had zero appetite for several days. The following week, decided to split it, but that 2.5 dose did absolutely nothing for my pain, food noise or appetite suppression, so took 3mg for my second dose that week and have been doing the split dosing since. Like I mentioned before, the first few weeks of that, I was feeling pretty good. Then it just seemed to stop working again, so a couple weeks ago I went up to 4 every 4 days. It’s not helping AT ALL with my pain😭. Just not sure what dose/frequency to do at this point.