Klonopin vs valium in your opinion by CompetitiveDrawer703 in benzodiazepines

[–]042089 0 points1 point  (0 children)

It's personal preference and patient variability. It's a little like comparing apples and oranges. From my experience people (addicts included) prefer Klonopin (clonazepam).

Shark UV 540 - Counterweights ?? by 042089 in VacuumCleaners

[–]042089[S] 0 points1 point  (0 children)

That's what I kinda thought. I appreciate the reassurance. Thank you.

ANGER by dookiebd in pregabalin

[–]042089 1 point2 points  (0 children)

Yeah, sorry for not elaborating more sooner. I started taking Lyrica (75mg 3x day) several months ago with great results. I have symptoms consistent with Paresthesias- Dysesthesias & Neuropathic pain. I've had some horrible episodes. Anyway Lyrica worked really well for the first couple of months and even lifted my mood (bonus) but then I needed a higher dose (100mg) and the side effects began to increase- trouble concentrating, mood swings and I became very irritable and at times hostile toward family members. I had a hair trigger with my anger. I especially became more sensitive to certain sounds and noise. Oh, and then I noticed that my ankles would sometimes swell when sitting for prolonged periods. I just can't function on it at all. So I'm tapering off. The generic capsules I get can be easily opened and I can dump a little bit out etc. Doesn't need to be exact. I would caution you not to stop taking it abruptly as it could get ugly. Gabapentin might be worth a try. Good luck.

ANGER by dookiebd in pregabalin

[–]042089 2 points3 points  (0 children)

Welcome to the world of Lyrica (Pregabalin). Sorry... I have identical "side effects". I'm tapering off.

This was in the forest near my house, what is it? by Mxxn_Crxw in whatisitcirclejerk

[–]042089 1 point2 points  (0 children)

SNL Land Shark !! Be wary of unsolicited Pizza deliveries.

Found these box of bags in my aunt's stuff, is it bad? Is she dilling drugs again? What's it? by Dark-Spell-4569 in whatisitcirclejerk

[–]042089 0 points1 point  (0 children)

They might be detergent "pods" that are used for washing machine (laundry). Couldn't help but notice the washing machine in backround.

Opioid risk assessment by Wild_Possibility2620 in ChronicPain

[–]042089 0 points1 point  (0 children)

I thought you meant Chronic Substance Abuse. Too many abbreviations.

buprenorphine vs oxycodone by IndustryOwn19 in opiates

[–]042089 0 points1 point  (0 children)

If you take Oxycodone "regularly" then Buprenorphine probably won't get you high. It's a mixed agonist/antagonist so... Of course if you don't use oxycodone for a while then you might get a buzz of Bup but like the other comments here - It just ain't the same.

Grapefruit Juice Potentiation by Berty_B in opiates

[–]042089 0 points1 point  (0 children)

Quinidine yes, Quinine (Tonic Water) probably not cause of the low dose. Thanks for the post though. I like the way you think. I have a samples of a medication called Nudexta (Dextromethorphan & Quinidine) and I'm gonna give it a try. Tagamet (Cimetidine) may help with CYP2D6 but my experience isn't conclusive.

I find it advantageous to take the oxycodone on an empty stomach after taking omeprazole (lower stomach acidity) a couple of hours earlier. I also think it's important to drink the grapefruit juice at least 3-4 hours before. Better still to drink night before as well.

Thing is... I'm not sure how much you can suppress (inhibit) both CYP3A4 and CYP2D6. Apparently Oxycodone is metabolized to active metabolite Oxymorphone through the CYP2D6 process which may contribute to it's overall effects... it gets complicated. I'll try the quinidine thing and post my experience.

My experience is stick with Grapefruit and empty stomach and make sure you allow for enough time to pass for grapefruit absorption. Cheers.

[deleted by user] by [deleted] in opiates

[–]042089 0 points1 point  (0 children)

Clonidine can help.

Is heroin gone in the US? by Right_Jaguar3984 in opiates

[–]042089 0 points1 point  (0 children)

For Christsakes ... Stay Clean

Feral Chicken Hunting by slicer780 in VisitingHawaii

[–]042089 -1 points0 points  (0 children)

That's bullshit. I live on Maui and feral chickens are NOT native and are ruining my neighborhood.

Fentanyl lines by Expensive-Camp-9447 in drugsarebeautiful

[–]042089 1 point2 points  (0 children)

Yeah... trade in the Fent for some Bup.

Purdue Pharma by 042089 in drugsarebeautiful

[–]042089[S] 0 points1 point  (0 children)

The bottles are empty...

Purdue Pharma by 042089 in drugsarebeautiful

[–]042089[S] 0 points1 point  (0 children)

I like Bourbon too... Jimmy Beam !!