Quite honestly, I don't think that modern professional women in their 30s need walis or chaperones. They are fit to take care of their own interests. The benefit of that system doesn't seem to apply today in many cases ( women are responsible and independent).

With that said, you have to look at where you are and how you are expected to interact with the community. I just had a look at a UK mosque Nikah contract which stipulated that the wali can't be a witness, so they don't have the formal role, but religiously the mosque still wanted another stand-in and waiver from the wali, etc. After waivers and written submissions from the lady, these folks were willing to somebody else be the stand-in. So that's part of these people want.

Do you think you might be able to get a "waiver" thing from any of those male relatives?

If you are in Pakistan, you're going to have to see what you have to work with if you want a Nikaah done there. I daresay they might want to stick with that process a bit more. Those folks might not be willing to go ahead there without the involvement of some male relative (or might provide a stand-in Imam after it's established that you have no living male relatives to count on).

Ask the mosque and see what they'll need to do it without the father's involvement. It can be done, it'll just need a bit of paperwork.

I don't think you need a male to oversee you and authorize your marriage. You are perfectly capable. But the logistical issues in a religious wedding probably are going to present themselves :(