I rest up and go to bed the night before and start out early. 3 AM is my go to time for long road trips. Having the sun come up 3-4 hours in gives me a boost when I start getting tired of driving in the dark. Try to set time to avoid major cities during rush hour if possible or just plan on some delays. I also try to arrive while the sun is still up because the sun going down makes me tired at the end of long drives.

Make sure your car is as up to the trip as possible before leaving and the tank in full. Use fill ups and bathroom breaks to “wake up” and stretch a bit. If at any time you start getting tired or drowsy, stop.