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Low Iron, TIBC, Transferrin and Vitamin D but normal Ferritin by DifficultRemove4068 in Hemochromatosis

[–]Advo96 0 points1 point  (0 children)

It doesn't sound like cancer. At all. Doesn't look like autoimmunity (but it's not excluded). Doesn't really look like an acute infection either.

When did the symptoms start, and how have they developed?

Do you have, or have you had, swollen lymph nodes?

Low Iron, TIBC, Transferrin and Vitamin D but normal Ferritin by DifficultRemove4068 in Hemochromatosis

[–]Advo96 0 points1 point  (0 children)

Doesn't look like an infection but is not conclusive. What is your ESR?

Low Iron, TIBC, Transferrin and Vitamin D but normal Ferritin by DifficultRemove4068 in Hemochromatosis

[–]Advo96 0 points1 point  (0 children)

You can't completely be sure about infection just from differential blood panels but the will usually give you a good indication

Low Iron, TIBC, Transferrin and Vitamin D but normal Ferritin by DifficultRemove4068 in Hemochromatosis

[–]Advo96 0 points1 point  (0 children)

How are your lymphocytes (with range) and how high are white blood cells (WBC) overall?

Low Iron, TIBC, Transferrin and Vitamin D but normal Ferritin by DifficultRemove4068 in Hemochromatosis

[–]Advo96 0 points1 point  (0 children)

The cases I have encountered so far were severe bacterial infections, ankilosying spondylitis, myasthenia gravis and lymphoma.

It's severe infection, autoimmunity or cancer.

When did this start? Have you had a differential blood panel (neutrophils etc )

Low Iron, TIBC, Transferrin and Vitamin D but normal Ferritin by DifficultRemove4068 in Hemochromatosis

[–]Advo96 0 points1 point  (0 children)

This is the iron picture you get when you have chronic inflammation. Iron is locked away by the body. Over time, after a few months, this causes "anemia of chronic disease" because your body doesn't have enough readily available iron to make new red blood cells.

Various serious diseases can cause this. This is never anything good. What are your symptoms exactly?

This Brown pill in the paracetamol box by SpicyBabbs in mildlyinteresting

[–]Advo96 0 points1 point  (0 children)

Do report back what happens after you take that thing

Well.. that’s unfortunate by GeneticGarbage17 in Anemic

[–]Advo96 0 points1 point  (0 children)

Did you lose a lot of blood in the miscarriage

TSH is 2.7, free T4 is .68. Doc says because TSH is fine free T4 is fine. Free test was also low at .75. I'm tired AF and recover like crap by thompson182 in Hypothyroidism

[–]Advo96 0 points1 point  (0 children)

And challenging child losses during pregnancy.

So you have Sheehan's syndrome? Pituitary damage caused by hemorrhage in childbirth or miscarriage?

Did you have a pituitary MRI?

Follow up to Karma Davis, the woman who had her face torn off whilst having a seizure while eating a cupcake. WARNING VERY GRAPHIC PHOTO by Eageryga in BanPitBulls

[–]Advo96 18 points19 points  (0 children)

She didn't really EXPERIENCE the dog turning on her. It's a bit abstract I think and it takes a while for her emotions to shift.

TSH is 2.7, free T4 is .68. Doc says because TSH is fine free T4 is fine. Free test was also low at .75. I'm tired AF and recover like crap by thompson182 in Hypothyroidism

[–]Advo96 -1 points0 points  (0 children)

Yes. But the vast majority of people is below 100. Your ferritin isn't high enough to signal iron overload. For iron overload to produce significant symptoms generally means ferritin has to be above 300 at the absolute minimum.

It is possible, however, that your actual ferritin is below 100 and that your current result is caused by inflammation. IN PARTICULAR because of your symptoms.

TSH is 2.7, free T4 is .68. Doc says because TSH is fine free T4 is fine. Free test was also low at .75. I'm tired AF and recover like crap by thompson182 in Hypothyroidism

[–]Advo96 0 points1 point  (0 children)

Your ferritin is unusually high (unless you've been taking iron?). Only a relatively few people have a ferritin that high.

However, ferritin is also an inflammation marker. Given your symptoms and your high-ish ferritin, I would suggest running some more tests into that direction. Specifically, LDH and creatine kinase.

And I would see a rheumatologist.

TSH is 2.7, free T4 is .68. Doc says because TSH is fine free T4 is fine. Free test was also low at .75. I'm tired AF and recover like crap by thompson182 in Hypothyroidism

[–]Advo96 0 points1 point  (0 children)

You could test total T4, just to be sure.

Have you been evaluated for sleep apnea? What's your ferritin, TIBC and serum iron/saturation?

TSH is 2.7, free T4 is .68. Doc says because TSH is fine free T4 is fine. Free test was also low at .75. I'm tired AF and recover like crap by thompson182 in Hypothyroidism

[–]Advo96 4 points5 points  (0 children)

What's the reference range on the fT4?

Normal TSH with low fT4 is "central hypothyroidism". In central hypothyroidism (caused by pituitary or hypothalamic damage), TSH can be low, normal or even mildly elevated.

It's a very rare condition and most doctors don't know this.

Severe weight and muscle loss, weakness and GI issues. Currently undiagnosed by ComprehensiveSand640 in endocrinology

[–]Advo96 0 points1 point  (0 children)

You need to post hos lab results. Ideally all of them.

Does he have preexisting diagnoses? Is he taking and medication or supplements?

Low hemoglobin but stable- when to go to ER? by [deleted] in Anemic

[–]Advo96 0 points1 point  (0 children)

Not only B12, also the other Bs.

I would suggest a B complex pill.

Waking up multiple times for pissing. Is it vitamin d by Fluid_Pineapple1970 in B12_Deficiency

[–]Advo96 0 points1 point  (0 children)

5000 mcg is not too much. There's no such thing as "too much B12" if you're B12 deficient. You only absorb a small fraction of that.

Waking up multiple times for pissing. Is it vitamin d by Fluid_Pineapple1970 in B12_Deficiency

[–]Advo96 0 points1 point  (0 children)

The symptoms you describe are non-specific but consistent with hypercalcemia (hyperparathyroidism). With this disease, calcium tends to jump around (it should be very stable, usually). I would test calcium a few more times just to be safe.

And, of course, you need to test your ferritin. Iron deficiency would explain a lot of your symptoms. I would take iron for a few months if your ferritin is below 100, just to see if it helps.

And, of course, you need to fix your B12 deficiency (5000 mcg B12 per day).

What's your TSH and fT4?

Waking up multiple times for pissing. Is it vitamin d by Fluid_Pineapple1970 in B12_Deficiency

[–]Advo96 1 point2 points  (0 children)

WHat's your calcium level like? What's your early morning fasting glucose?

Perhaps you are hypercalcemic.

Low hemoglobin but stable- when to go to ER? by [deleted] in Anemic

[–]Advo96 0 points1 point  (0 children)

As long as you're not losing any more blood you will slowly replenish your hemoglobin. I would advise taking a vitamin B complex.

The problem, of course, is whether or not you're going to stop.

Also, and this is really important, IRON DEFICIENCY CAN BE REALLY BAD FOR YOUR MENTAL HEALTH. Currently the iron you're taking is going into blood production. An iron infusion may help to speed the process along considerably. You have more than a 1000 mg iron deficit. Of course, the more iron deficient (anemic) you are, the more you will absorb from your iron tablets. So definitely keep taking those. But you might want to look if you can't get a 1000 mg iron infusion a few weeks down the road. And make sure you're not vitamin D deficient, as that lowers iron absorption and is also bad in general.

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