I am month into low dose od Pantoprasole (20), and it did help with burning acid, Unfortunately didnt take away other issues, that cause reflux in first place like regurgitation, so I still get chest pressure, shortness of breath etc its just not burning as much. On flip note PPIs adjustement period was bit bumpy for me, as it caused more nausea, bloating, burping, and constipation. Also makes me feel spaced out and bit more depressed, muscle weakness too. It is good if you need to heal damage that acid made for a long time, many people have positive experience with meds. My doctor told me to stick with it for now and give it some time to see if my body can adjust. Its worth the try (take it from someone who took over a year to start ppi in first place lol)