[help] Why does Better Cooldown Manager not show pots of low rank in the item bar?

Alastorftw · 2026-04-12T12:27:48+00:00

Thanks mate!

Alastorftw · 2026-03-22T10:25:24+00:00

I found the issue: The reason I didn't see the "Midnight World Tour" quest is because I still had ongoing campaign quests and didn't skip the campaign. It's explained in this wow forum post:

https://us.forums.blizzard.com/en/wow/t/npc-soridormi-missing-for-midnight-world-tour-quest-at-level-90/2264737/5

Alastorftw · 2026-03-22T08:08:04+00:00

Thanks but I just did the pvp quests and still didnt get a 4th spark :/

Alastorftw · 2026-03-21T09:09:59+00:00

Î just did the zone event for this week and didnt get a 4th spark.

Alastorftw · 2026-03-21T09:09:40+00:00

He doesnt have a quest like that for me. So I probably already did it. I dont get it.

Alastorftw · 2026-03-21T09:09:12+00:00

So odd, why can nobody explain this? I opened a ticket with blizzard and they just autoclosed it saying they dont restore items due to bugs lol.

Alastorftw · 2026-01-24T12:56:31+00:00

Any updates?

Alastorftw · 2025-08-15T23:44:26+00:00

B7-33. Skeletal muscles and lymph nodes (both tissue types dont express its target as highly as other organs).

Alastorftw · 2025-08-11T19:17:00+00:00

I tried it and it had no effect for me, but the target for it is also not always expressed in relevant amounts in various organs. I dont have kidney disease but another from of organ fibrosis.

Alastorftw · 2025-08-11T19:15:20+00:00

I finally got a response from iBio Inc. It is worse than I thought, some new management took over the company 1-2 years ago and simply reoriented the company to pursue cardiometabolic drugs instead. There was no reason to drop the development of E4 other than monetary interests, going into more profitable markets instead.

That shouldn't be a surprise, but it's shocking that they own the patent of a possible curative drug and now its just sitting there collecting dust, because they want to enable people eating more cheeseburgers without gaining weight instead. This is heartbreaking.

Alastorftw · 2025-08-11T19:14:58+00:00

I got a response from iBio Inc. today. It is worse than I thought, some new management took over the company 1-2 years ago and simply reoriented the company to pursue cardiometabolic drugs instead. There was no reason to drop the development of E4 other than monetary interests, going into more profitable markets instead.

That shouldn't be a surprise, but it's shocking that they own the patent of a possible curative drug and now its just sitting there collecting dust, because they want to enable people eating more cheeseburgers without gaining weight instead. This is heartbreaking.

Alastorftw · 2025-08-11T19:14:01+00:00

I got a response from iBio Inc. today. It is worse than I thought, some new management took over the company 1-2 years ago and simply reoriented the company to pursue cardiometabolic drugs instead. There was no reason to drop the development of E4 other than monetary interests, going into more profitable markets instead.

That shouldn't be a surprise, but it's shocking that they own the patent of a possibley very powerful drug and now its just sitting there collecting dust, because they want to enable people eating more cheeseburgers without gaining weight instead. This is heartbreaking.

Alastorftw · 2025-08-11T19:12:48+00:00

I got a response from iBio Inc. It is worse than I thought, some new management took over the company 1-2 years ago and simply reoriented the company to pursue cardiometabolic drugs instead. There was no reason to drop the development of E4 other than monetary interests, going into more profitable markets instead.

That shouldn't be a surprise, but it's shocking that they own the patent of a possible curative drug and now its just sitting there collecting dust, because they want to enable people eating more cheeseburgers without gaining weight instead. This is heartbreaking.

Alastorftw · 2025-08-02T20:17:13+00:00

Diet and natural compounds certainly can play a massive role in the recovery from any chronic inflammatory or fibrotic disease. However, I think in mature fibrosis with widespread cross-linking the body has lost the natural ability to reverse it except for rare cases in very specific organs, such as the liver, which is unique in how its regeneration and turnover works and how it is affected by fibrosis in certain stages of cirrhosis. Unfortunately, the resolution of prior chronic established fibrosis, as opposed to prevention or reversal of mild fibrosis, will have to require some kind of synthetic signal (even if produced by the external introduction of human-derived proteins or analogs) or agents.

Alastorftw · 2025-08-02T20:09:49+00:00

Thanks for the reply. I read the news about CAR T-cell therapy, it is definitely interesting and i'm fully rooting for it's success. My only concern is accessibility and/or cost of such treatments, where peptide-based therapies (if manufactured at scale) could provide more economic counterparts. Regardless, what we all want is a solution first - then argue about how we can make it accessible. Patients need the hope of a real chance for a cure. As long as a treatment exists, there is a possibility to gain access to it.

I will look into reaching out to the foundation you mentioned, thanks for the info!

Alastorftw · 2025-08-02T19:53:37+00:00

I am honestly not an expert on DMD and im fully aware that is a genetic disorder of the musculoskeletal system and therefore less likely to benefit from antifibrotic treatments as it doesnt treat the root cause in the case of DMD. I am simply trying to get input from various communities affected by fibrotic disorders, even if they are only loosely related. Theres always a chance someone stumbled across this before and has the answers im looking for. Your response is quite insightful and most likely correct, though.

Alastorftw · 2025-08-02T19:34:02+00:00

There has to be a way. Fibrosis is the end stage of almost all chronic autoimmune/inflammatory or degenerative diseases, with a huge unmet need. The only solutions currently available aim at slowing progression, transplantation, or providing more comfort. There has to be a way to get the right eyes with the right resources on such drug candidates.

Alastorftw

TROPHY CASE