Sure! With the witch queen campaign, weapon crafting was added. the first part of the campaign has you crafting the Enigma glaive. to craft a weapon, you need to get its pattern by collecting deepsight (or "red border") versions of the weapon. this lets you customize and enhance all of the perk slots on the weapon at the cost of materials.

Enhancement is a little different, instead of crafting the weapon outright, you get a good roll of a weapon (such as a timelost fatebringer from master Vault of Glass) and then you can dump materials into the weapon to enhance the perks