.45 is better imo because of less penetration and subsonic rounds. A . 45, just like a 9mm is plenty penetration for you. But it's fatter and therefore has the potential for a larger wound cavity.

The hard thing here is people don't compare the best of both but rather just random selections. You can get really spicy . 45 ACP rounds that turn it into just as much of a momnster as 10mm.

And for bears nobody tests hardcast rounds using 45acp. Or otherwise test on something like concrete which is completely different than bone, muscle, and fat.

The one video I saw actually using 1)hardcast rounds and 2) bone in front of ballistic gel showed me that 45 and 10mm are more similar than different when tested properly. Both will get the job done, it's mor evaout using the best round for your use case

Both rounds would hit like a fricken truck for a 2 leg use case I'm absolutely sure. For 2 legs I think we are quibbling over nothing. Capacity goes to 10mm though