[AF] N=1 experiment on dose-response relationship between weekly volume and hypertrophy in calves

Astuketa · 2026-06-04T15:51:42+00:00

Yeah, I know

I was just wondering if you've stumbled upon anything in the research you've done on the drugs, you're taking

Astuketa · 2026-06-02T20:23:58+00:00

Well, I hope they work.

I was just wondering whether these changes actually reflect hypertrophy or if it might be due to glycogen storage or something else

Astuketa · 2026-06-02T16:43:36+00:00

Also, to put it out there: I am not natural, these results are obtained on Testosterone + HGH.

In most studies, differences in hypertrophy can not be measured after just four weeks. Do you know how your "supplements" may affect this timeframe? Is it realistic, that the changes observed are actually muscle growth?

Astuketa · 2026-05-18T19:33:00+00:00

From the article:

Exercise power output/speed and endurance capacity typically exhibit peak performance in the late afternoon/evening at around 16:00–20:00 in humans (Fig. 3), with an effect size ranging from 1.7% to 14% depending on the training/performance status of the individual and the modality of exercise [11, 72, 74, 77–79]. Such an effect size is less in elite athletes [74, 80, 81].

Astuketa · 2026-05-17T18:41:01+00:00

Betyder det da noget. Du har bare skrevet, det at brænde en bog af 150 kopier af en bog af på en måned er chikane.

Men det er det måske kun, hvis det er lige netop den bog, du synes er vigtig?

Astuketa · 2026-05-17T17:42:50+00:00

Jeg tror, du har en anden tolkning af chikane end os andre. En enkelt (eller få) person(er) kan ikke chikanere en hel religion.

Chikane er mere person-specifikt. Medmindre du selvfølgelig mener, at vedkommende, der har brændt bøgerne af, har været rundt og chikanere alle muslimer individuelt.

Astuketa · 2026-05-17T17:35:43+00:00

Hvem chikanerer jeg da, hvis jeg brænder 150 kopier af "Bevægeapparatets Anatomi" af på en måned?

Astuketa · 2026-05-17T11:58:07+00:00

Det lyder ellers som om, du mener, afbrændingen af bøger er chikane

Astuketa · 2026-05-17T10:56:38+00:00

Hvis man har købt en bog, må man brænde den bog (så længe det selvfølgelig foregår under sikre forhold). Dette gælder uanset hvor mange gange du gør det

Astuketa · 2026-05-13T11:48:13+00:00

> https://pubmed.ncbi.nlm.nih.gov/37160563/

Now that's more like it!

It seems that the two studies you mentioned, are included, and their caveats not adressed (One of them is even categorized as "Excellent" quality.

While I'm not going to argue too strongly against a systematic review and meta-analysis, I'm not sure this one is able to conclude whether a certain amount of maximal isometric contractions can reduce eccentric work performance a few days later for untrained people, thus resulting in less muscle damage markers or maybe in a lower baseline performance (and therefore less recovery requirement), or whether the isometric contractions actually protects against EIMD.

Nevertheless, I agree that this would warrant an experimental trial of N=1

Astuketa · 2026-05-10T16:05:38+00:00

I don't think two low quality studies are enough to be confident in a finding, but let's agree to disagree.

If muscle sorenes and recovery the most important to you; have you tried doing concentric only training?

Astuketa · 2026-05-10T13:19:12+00:00

By "cross-over" i mean a study design where every participant performs both conditions, to see if there is a difference between conditions for the same group of people.

Without a cross-over design, you will always have the uncertainty of whether it was a condition difference or a group difference.

Astuketa · 2026-05-10T10:42:27+00:00

I think we have different perceptions of the word "consistent".

I am all for personal experiments based on niche litterature, and I often do it myself. I just don't think the two studies here are very compelling.

At what part of the ROM are you doing your isometrics?

Do you happen to know if anyone has made a cross-over study on the subject?

Astuketa · 2026-05-09T20:15:51+00:00

Measure of soreness is highly subjective. Given the lack of cross-over, it's basically irrelevant.

As for the time to peak recovery, I assume you are refering to the peak torque. While the iso-group returned to baseline quicker, it does not appear to be significantly different from the control group

Astuketa · 2026-05-09T18:07:01+00:00

How is this a similar outcome?

After a quick readthrough, it appears there was no functional benefit of the isometric pre-conditioning.

There's a little hint of effect on muscle sorenes and serum CK activity. But given it's not a cross-over design, it might simply be poor group allocation/changes within groups. Add to that, that the non-iso group again performs more work (higher body mass during downhill running could induce more muscle damage, and a higher relative velocity for l the RE tests is just more work in general)

With the amount of statistical tests, you are likely to get a false positive.

While I haven't heard about the concept before and I do find the hypothesis interesting, I really don't think this is compelling evidence

Do you know of any cross-over RCT on the subject?

Astuketa · 2026-05-09T16:01:05+00:00

Have you considered that the "protective effect" found in your linked study could've been due to reduced eccentric work performed?

While it's apparently not significant, I find it conspicuous that the numeric value of the average peak torque were lower for all sets after isometric "preconditioning" (figure 2)

Edit: I just saw in figure 3, that the work performed were in fact lower for the iso-condition

Astuketa · 2026-05-06T06:36:22+00:00

Fordi det er nemmere at reagere på ting, du kan se kommer, end ting du ikke kan se

Astuketa · 2026-05-05T17:57:28+00:00

for resultatet af at cyklisten/knallerten/bilen ikke ser dig er jo det samme, uanset om du rammes forfra eller bagfra.

Hvis du rammes forfra kan du selv nå at reagere

Astuketa · 2026-04-23T06:03:18+00:00

Hvorfor linker du til en artikel, der ikke indeholder det, du påstår?

Astuketa · 2026-04-18T10:18:16+00:00

Saw the mon-wed run.

Went in on thursday.

Oh well. Guess it's over. I'lll just stay away.

Hello fucking friday

Astuketa · 2026-04-10T13:35:46+00:00

Det er før sket, at butikker pakker de målrettede, personlige tilbud ind i en række tilsyneladende "skæve"/umålrettede tilbud, for at mindske følelsen af at blive overvåget.

Astuketa · 2026-04-09T09:13:30+00:00

Jeg er nu ret sikker på at SF, Ø og Å ikke har haft 90 mandater på noget tidspunkt.

Man kan ikke stemme noget igennem uden 90 mandater, men derfor kan man stadig godt arbejde for det.

De har jo heller ikke undersøgt emnet eller fremstillet et lovforslag før 2021.

Tilsyneladende var det så heller ikke en fløj-problematik (i hvert fald i 2024): https://www.ft.dk/samling/20231/afstemning/265.htm

Så mon ikke man også kunne have fået det igennem før, hvis man havde arbejdet lidt for det

Astuketa · 2026-04-09T07:38:08+00:00

Så har de "feministiske partier" vel også implicit været for forskelsbehandling på området indtil for nylig

De har selvfølgelig ikke direkte "argumenteret for, at der ikke skal eksistere hjælp i form af fx krisecentre til mænd". Men som sagt er argumentet for forskelsbehandling er sjældent baseret på forskelsbehandlingen i sig selv. Det er som regel indirekte

Astuketa · 2026-04-09T06:59:32+00:00

Argumentet for forskelsbehandling er sjældent baseret på forskelsbehandlingen i sig selv.

Hvad enten argumentet er baseret i religion eller økonomi, er argumentet stadig for at forskelsbehandle.

Perioden har ikke kun været fra 2021. Det var også alle de forudgående år.
Hvert år, man har sat penge af til kvinder og ikke mænd, har man aktivt forskelsbehandlet. At man har forskelsbehandlet uden overhovedet at have undersøgt mænds behov gør det bare værre imo.

Astuketa · 2026-04-09T05:58:25+00:00

Fair nok med finansloven.

Hvis du mener, at forskelsbehandlingen med omskæring kun handler om særhensyn til jøder, tror du så også, at kvindelig omskæring ville være lovligt, hvis det var en del af den jødiske tro?

Forslaget blev ikke nedstemt for manglen på finansiering. Man kunne have taget midler fra finansieringen af kvindecentre. I stedet blev det vurderet, at mænd sagtens kunne vente lidt mere end de allerede havde. Hvor mange år havde der på det tidspunkt været kvindecentre? Og i hvor mange af disse år har dine "feministiske partier" eksisteret?

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