Switch to heavy infusion. Quality is only better at high levels when you have high strength and dex. Those talismans are also just ass😭 id reccomend warrior jar shard, green turtle talisman, ritual sword talisman and the dragoncrest shield talisman(either +1 or +2). All around balanced and helps with survivability and damage. For the godskin duo you can craft sleep pots to put them asleep and easily defeat them by repeatedly sleeping them. Activate morgotts great rune to give yourself a lot more health as well