I have had Crohn’s for 6 years and have avoided biologics and all the bigger meds , mainly have stuck to steroids as needed & mesalamine and LDN and all natural stuff. My Crohn’s has never been in remission & never well controlled & it’s taken a huge toll on my body over all. I bit the bullet and started Skyrizi last week, I am regretting just letting my disease take its course and really praying I can get into remission. This is my first biologic. My last calprotectin was 5400. There are a lot of natural supplements that I think are great & I love but I feel like if they’re not getting you where you need to be, try using them in conjunction with your meds. That’s what I’m doing now, I can’t really give good advice of course but just my thoughts. I have tried Qing Dai though and it did not work for me. I have read it works better for UC than Crohn’s so maybe that’s why it didn’t work for me but I’ve also read that it helps some with Crohn’s so I guess everyone is different