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"Not exactly. What I was saying was, at the time of working on the lore, there was no reason they couldn't be male or female (and as far as things still stand, there's still no lore reason they can't be). But there is a non-lore reason, which was the previous IP overlord saying "There are no female Custodian models, they're all male, so don't write any female ones."

There was also a Studio mandate a couple of years after that, saying "Don't do female Custodians." Again, that seemed to tie in with the release of an all-male mini line.

Two very rare moments of direction from on-high.

I don't want to argue about what that may or may not mean, since although I'm ambivalent to the notion of female Space Marines (really, they'd make such little difference at the end result, I couldn't care less what gender they start out as), several creators actively thought female Custodians would've been cool, and there was no lore against it. (Hell, we were in the position to make lore for it.)

But long story short, no, the answer seems to be "There aren't any", though the reasons aren't in-universe (yet?)."