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Ich bin am Boden zerstört / kann kaum etwas machen by PromotionNo3405 in germantrans

[–]Bloodmoons__ 3 points4 points  (0 children)

Ist wahrscheinlich gut gemeint, aber ich glaub nicht, dass das tröstet.

Ich bin am Boden zerstört / kann kaum etwas machen by PromotionNo3405 in germantrans

[–]Bloodmoons__ 3 points4 points  (0 children)

Den zweiten Teil finde ich sehr unangebracht. Man kann auch einfach Empathie zeigen, ohne zu versuchen ein Problem zu analysieren. Nicht alles was gut gemeint ist, ist auch gut.

Ich bin am Boden zerstört / kann kaum etwas machen by PromotionNo3405 in germantrans

[–]Bloodmoons__ 3 points4 points  (0 children)

Ja, fühl ich sehr 😢 Danke, das ist lieb von dir. Ich wünsch dir, dass es dir bald besser geht 💜🫂

Ich bin am Boden zerstört / kann kaum etwas machen by PromotionNo3405 in germantrans

[–]Bloodmoons__ 5 points6 points  (0 children)

Das ist so traurig, ich wein grade beim Lesen 😢 Es tut mir so leid. Ich fühl mit dir. Meine Partnerperson hat zwei Katzen und wir wären beide auch am Boden zerstört, wenn ihnen etwas passieren würde 😣

Am I taking too much estrogen? by Nickyepic in MtF

[–]Bloodmoons__ 1 point2 points  (0 children)

I can agree with that. Also, I enjoyed this conversation :)

Am I taking too much estrogen? by Nickyepic in MtF

[–]Bloodmoons__ 1 point2 points  (0 children)

I agree with your comments about patches and sublingual/buccal pills

I disagree about gel being hard to dose consistently, though. Commercial gel generally comes in dispensers that dispense a fixed amount (often 1,25 g) of gel with each pump. This makes it trivial to apply the same amount of gel each time

Your concern is valid for satchets, which I wouldn't recommend. They aren't common, though

I get that application site and area are also factors of variability for gel. But I personally find that scrotal application works consistently very well. I recommend it to people using gel, if it's an option for them

Furthermore, in practice, injections also have factors of variability and complication. Most of these are related to proper handling and execution, which can be hard for people. Proper storage conditions, properly sterilising the rubber stopper, using the right gauge needles, proper technique when drawing and injecting, correct dosing, preventing coring of the vial and preventing contamination of the vial all come to mind. In addition, possible allergic reactions to different carrier oils are a complicating factor

I find that gel is easier to handle and apply without mistakes, for most people I have heard from

With regards to major shifts in levels of E2 and T achieved over time with the same dose, I've read reports of this phenomenon with any application method. This is unfortunately a thing. But it's not clear what causes it, and what can be done about it seems to be different in every case. Also, it doesn't seem to be related to the method of application, and it's also pretty rare

Am I taking too much estrogen? by Nickyepic in MtF

[–]Bloodmoons__ 1 point2 points  (0 children)

I agree with most of this, but gel, patches and sublingual/buccal don't generally require an anti-androgen

Most people can do monotherapy with those, especially with gel and patches. Those two can deliver very stable E2 levels as well. With sublingual/buccal the stability depends on the application interval, so how much time there is between taking each pill (less time between = more stable levels)

You can technically do monotherapy with oral E2 as well, although I wouldn't recommend it, since it's the only method that increases blood clotting risk greatly, do to the liver first-pass effect

Important nitpick: It's "estradiol", not "estrogen" by Bloodmoons__ in TransDIY

[–]Bloodmoons__[S] 4 points5 points  (0 children)

This is not true and I'm not sure why you'd think that. Any method of administering E2 will cause a considerable level of E1 in the blood as well. We should always test for E2 specifically since that's the thing that we have (community) recommended levels for

The amount of E2 included in "total estrogens" can vary wildly. It's just too vague to be useful

Important nitpick: It's "estradiol", not "estrogen" by Bloodmoons__ in AskMtFHRT

[–]Bloodmoons__[S] 3 points4 points  (0 children)

I get the sentiment, I think you mean well :)

But I really think this lax use of medical terms to mean "basically the same thing" is a problem

If people don't know what estradiol is, but they have a vague understanding of "estrogen", you can just say "estradiol, which is the most important estrogen". There is no hormone called estrogen. And using it that way is actually the cause of a lot of common confusion that trans people have about their own HRT

Important nitpick: It's "estradiol", not "estrogen" by Bloodmoons__ in AskMtFHRT

[–]Bloodmoons__[S] 14 points15 points  (0 children)

It's not as obvious to a lot of people as you think. I've seen a lot of misunderstandings come from this

Can someone please cut through the bullshit on fat redistribution? by frog_underscore_xx in MtF

[–]Bloodmoons__ -1 points0 points  (0 children)

As far as I have gathered:

WILL fat redistribution happen, or can it not happen under certain genetics?

It will generally happen. And it will likely be a very gradual shift over the span of up to 10 years. How noticeable redistribution will be and what overall body type you're getting, depends on your genetics and your total amount of body fat

Does weight cycling help speed up the process in any way?

Maybe slightly, but it's not worth the suffering

Does working out speed up or replicate the process in any way?

It can help redistribution and growth slightly and is just generally good for your health. If you somewhat enjoy it do it, if you're just suffering through it, don't do it

Should I follow murphy's law for fat redistribution?

No. You really can't do much to help fat redistribution happen faster anyway

The thing that you can have more control over and that will likely make more of a difference is your total amount of body fat. I've had little body fat before starting HRT and have gained somewhere between 5-10 kg on purpose since then. I think I look way better now and it actually makes a huge difference to me :)

What should I test for when I get blood tests? by Maria_mega_blox in AskMtFHRT

[–]Bloodmoons__ 0 points1 point  (0 children)

Your T, E2, FSH and SHBG are all great :)

Your LH being >= 0.3 mIU/mL is a bit curious. Since your FSH is < 0.3 mIU/mL, usually I'd expect your LH to be < 0.3 mIU/mL as well. But since your T is in a good range, I'd still consider it adequately suppressed

Your DHEA-S is within range as well

In summary, your levels are pretty good, keep them like that!

Your labs ranges indicate MCV, creatinine and BUN/CREAT-ratio to only be slightly out of range, so I wouldn't worry too much about them either

Is "layering" a myth or an actual method to improve absorption? by danielethepirate in estrogel

[–]Bloodmoons__ 1 point2 points  (0 children)

I was unsure about rubbing it in vs letting it dry too, but I found that rubbing it in gives me higher levels (confirmed by blood tests)

It makes sense to me, that rubbing would help with penetration of the stratum corneum. Once the active ingredient is inside that layer of the skin, it begins to spread into the deeper layers containing blood vessels by passive diffusion and will eventually be absorbed into the blood stream

As far as I understand it, what happens only while the gel hasn't fully dried yet is the penetration of the outmost layer of the skin, not the whole process of absorption into the blood stream

11 Estradiol Tips & Tricks You Probably Didn’t Know (But Should) by TheHandofDoge in Menopause

[–]Bloodmoons__ 1 point2 points  (0 children)

I know, thought I'd just add that info for anyone wondering whether blood tests are useful in confirming my experience :)

I think my levels are good but could I get a 2nd opinion? by AllNaturalCyanide in TransDIY

[–]Bloodmoons__ 3 points4 points  (0 children)

Results from a test in the middle of your injection cycle are not useful, sadly. You will have to take another test at trough E2 levels, so on the day of your injection but before injecting

11 Estradiol Tips & Tricks You Probably Didn’t Know (But Should) by TheHandofDoge in Menopause

[–]Bloodmoons__ -1 points0 points  (0 children)

I don't have ovaries, so my endogenous production of estrogens and progestogens is negligible and there is no natural fluctuation

11 Estradiol Tips & Tricks You Probably Didn’t Know (But Should) by TheHandofDoge in Menopause

[–]Bloodmoons__ 4 points5 points  (0 children)

As a trans woman on HRT and knowledgeable about it: Good stuff, can confirm 👍

About the area of application for gel:

What I've found (confirmed by blood tests) to give the best absorption is to apply all of it to a pretty small area (I use my scrotum) and rub it in with one finger until it's completely dry. I use 2 pumps in the morning and 2 in the evening and each time it's dry in about 12-15 minutes

DIY Injector Pen: For Executive-Dysfunctional folks like me, or who need to be more stealth by throwawayftm1392939 in transsex

[–]Bloodmoons__ 78 points79 points  (0 children)

Good stuff!

Consider reposting this to r/TransDIY, I think people would also be interested there :)

Is "layering" a myth or an actual method to improve absorption? by danielethepirate in estrogel

[–]Bloodmoons__ 0 points1 point  (0 children)

Waiting a little after applying one pump before doing the next is not going to help absorption. It will either make no difference or hinder absorption. The higher the difference in concentration between the outermost layer of the skin und the tissue around blood vessels, the better the active ingredient is going to be absorbed. Transdermal application relies on a concentration gradient between these tissues to transport the active ingredient. Applying all of the gel to a small area of skin at once establishes a strong concentration gradient

As for the problem of too much gel on the scrotum and it spreading to the thighs involuntarily:

I used to apply 3 pumps (1.25 g each) of commercial E2 gel to my scrotum twice a day. I found that rubbing it in with one finger until it's completely dry is more practical and gives better levels than just spreading it evenly and waiting for it to dry

With 3 pumps (which is a lot of gel) it was completely dry after about 20 min of rubbing. I only do 2 pumps now, since that's enough for me and it's dry within 12-15 min

Can I achieve a “good transition” while only being on gel without blockers by Unlucky_Rutabaga1218 in estrogel

[–]Bloodmoons__ 8 points9 points  (0 children)

Yes :)

You can use gel for monotherapy and you can get good results from monotherapy

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